4774-34-9 Usage
Uses
Used in Pharmaceutical Industry:
4-Hydroxypyrimidine-5-carbonitrile is used as a key intermediate in the synthesis of pharmaceuticals for its potential role in the development of new drugs. Its unique structure allows for the creation of compounds with specific biological activities, contributing to advancements in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Hydroxypyrimidine-5-carbonitrile is utilized as an intermediate in the production of pesticides. Its incorporation into these chemical formulations can enhance the effectiveness of pest control agents, thereby supporting agricultural productivity.
Used in Organic Chemistry Research:
4-Hydroxypyrimidine-5-carbonitrile also serves as a valuable building block in organic chemistry. It is used for the preparation of complex organic compounds, facilitating the exploration of novel chemical reactions and the synthesis of new molecular structures with potential applications across various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 4774-34-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,7 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4774-34:
(6*4)+(5*7)+(4*7)+(3*4)+(2*3)+(1*4)=109
109 % 10 = 9
So 4774-34-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H3N3O/c6-1-4-2-7-3-8-5(4)9/h2-3H,(H,7,8,9)
4774-34-9Relevant academic research and scientific papers
Preparation method of medical intermediate 4-chloro-5-cyanopyrimidine
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Paragraph 0009; 0022-0023, (2021/11/03)
The invention discloses a preparation method of a medical intermediate 4-chloro-5-cyanopyrimidine. The method comprises the following steps: carrying out ring closing reaction on a compound 2-cyano-3-ethyoxyl ethyl acrylate as shown in a formula (II) and a compound formamidine acetate as shown in a formula (III) in a protonic solvent in the presence of sodium alcoholate to obtain a compound as shown in a formula (IV); and carrying out a chlorination reaction with any one or two or more than two of phosphorus pentachloride, phosphorus oxychloride, thionyl chloride or phosphorus trichloride to prepare the compound 4-chloro-5-cyanopyrimidine as shown in the formula (I). The preparation method disclosed by the invention has the following beneficial effects that the synthesis route is short, the synthesis is convenient, the yield is high, the toxicity of raw materials is small, the environmental pollution is relatively low, and the advantages of high purity, high yield, simple operation and industrialization are achieved; and the product obtained by adopting the method disclosed by the invention is convenient to purify, high in purification efficiency and good in effect. The method is suitable for manufacturers for preparing the medical intermediate 4-chloro-5-cyanopyrimidine.
