477585-75-4

Upstream product

• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 195607-10-4 (S)-2-Formyl-azetidine-1-carboxylic acid benzyl ester 
• 501-53-1 benzyl chloroformate 
• 186593-56-6 (S)-1-benzyloxycarbonyl-2-azetidinemethanol 
• 25654-52-8 (2S)-1-(benzyloxycarbonyl)azetidine-2-carboxylic acid 

Downstream Products

• 477585-76-5 methyl (2R)-3-((1-benzyloxycarbonyl)azetidin-2-yl)propanoate 
• 477585-90-3 (3S,5R,1'R)-3-((t-butyldimethylsilyloxy)-(phenyl)methyl)-1-azabicyclo[3.2.0]heptan-2-thione 
• 477585-89-0 (3S,5R,1'R)-3-((t-butyldimethylsilyloxy)-(phenyl)methyl)-1-azabicyclo[3.2.0]heptan-2-one 
• 477585-79-8 (3S,5R,1'R)-3-(hydroxy-(4-nitrophenyl)methyl)-1-azabicyclo[3.2.0]heptan-2-one 
• 477585-96-9 (2R)-3-((1-benzyloxycarbonyl)azetidin-2-yl)propanoic acid 
• 477585-86-7 (3S,5R,1'R)-3-(hydroxy-(phenyl)methyl)-1-azabicyclo[3.2.0]heptan-2one 

Relevant academic research and scientific papers

Synthesis of chiral bicyclic azetidine derivatives

(2S)-N-Benzoyl-2-azetidinecarboxylic acid was converted into several derivatives of (5R)-1-azabicycloheptane via lactamization of 3-((2R)-azetidine)propanoic acid, subsequent aldol reaction and reduction. The structures of three stereoisomers of (5R)-3-(hydroxy-(4-nitrophenyl)methyl)-1-azabicyclo[3.2.0]heptan-2-one were determined by X-ray crystallography.