25654-52-8

Basic information

• Product Name: (S)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID
• Synonyms: (S)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID;(S)-1-Cbz-2-azetidinecarboxylic acid
• CAS NO: 25654-52-8
• Molecular Formula: C₁₂H₁₃NO₄
• Molecular Weight: 235.24
• Mol File: 25654-52-8.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 421.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.362±0.06 g/cm3(Predicted)
• PKA: 3.99±0.20(Predicted)
• CAS DataBase Reference: (S)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID(25654-52-8)
• EPA Substance Registry System: (S)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID(25654-52-8)

Safety Data

• Hazardous Substances Data: 25654-52-8(Hazardous Substances Data)

Usage

Uses

(S)-1-((Benzyloxy)carbonyl)azetidine-2-carboxylic Acid is an intermediate for the synthesis of Mugineic Acid Ammonium Salt (M792005). Mugineic Acid, a possible phytosiderophore of graminaceous plants, has iron chelation potency and antioxidant activity.

Upstream product

• 174740-81-9 N-benzyloxycarbonyl-(S)-(-)-2-azetidine-carboxylic acid 
• 501-53-1 benzyl chloroformate 
• 2133-34-8 (2S)-azetidine-2-carboxylic acid 
• 352018-67-8 (R)-4-N-benzyloxycarbonylamino-2-chlorobutyric acid 
• 186593-56-6 (S)-1-benzyloxycarbonyl-2-azetidinemethanol 
• 75315-63-8 N-(benzyloxycarbonyl)succinimide 

Downstream Products

• 144062-00-0 N-benzyloxycarbonyl azetidine-2-carboxylate methyl ester 
• 153704-88-2 (S)-1-benzyl 2-tert-butyl azetidine-1,2-dicarboxylate 
• 186593-56-6 (S)-1-benzyloxycarbonyl-2-azetidinemethanol 
• 864951-51-9 (S)-Azetidine-1,2-dicarboxylic acid 1-benzyl ester 2-((S)-2-cyclohexyl-1-methyl-ethyl) ester 
• 228867-83-2 (S)-1-(benzyloxycarbonyl)-2-azetidinemethanol-p-tosylate 
• 195607-10-4 (S)-2-Formyl-azetidine-1-carboxylic acid benzyl ester 
• 477585-75-4 (S)-2-((E)-2-Methoxycarbonyl-vinyl)-azetidine-1-carboxylic acid benzyl ester 
• 477585-76-5 methyl (2R)-3-((1-benzyloxycarbonyl)azetidin-2-yl)propanoate 
• 477585-96-9 (2R)-3-((1-benzyloxycarbonyl)azetidin-2-yl)propanoic acid 
• 88015-21-8 (S)-2-[(1S,2S)-2-Chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydro-pyran-2-yl)-propylcarbamoyl]-azetidine-1-carboxylic acid benzyl ester 
• 144062-03-3 (S)-4,4-Diphenyl-3-oxa-1-aza-bicyclo[3.2.0]heptan-2-one 
• 144062-05-5 (S)-2-(Hydroxy-diphenyl-methyl)-azetidine-1-carboxylic acid benzyl ester 
• 319918-73-5 (2S)-1-(Benzyloxycarbonyl)azetidine-2-carboxylic acid chloride 
• 1403954-15-3 C₃₈H₃₆N₄O₆ 

Relevant articles and documents

AZETIDOBENZODIAZEPINE DIMERS AND CONJUGATES COMPRISING THEM FOR USE IN THE TREATMENT OF CANCER

A compound of formula IV: as well as drug-linkers and conjugates comprising this compound, and the use of the conjugates in treating cancer.

FUMAGILLOL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making fumagillol compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.

NEW TETRACYCLINE DERIVATIVES AS ANTIINFECTIVE AGENTS

In accordance with one embodiment, the present invention provides a compound of general formula (I), stereoisomers thereof and/or its pharmaceutically acceptable salts thereof, which have antibacterial activity; with methods of treating infectious diseases in warm blooded animals employing these new compounds.