47765-29-7Relevant academic research and scientific papers
Simplified tetrandrine congeners as possible antihypertensive agents with a dual mechanism of action
Iturriaga-Vasquez, Patricio,Miquel, Raquel,Ivorra, M. Dolores,D'Ocon, M. Pilar,Cassels, Bruce K.
, p. 954 - 957 (2003)
A series of O- and/or N-substituted derivatives of (±)-coclaurine (1a) were synthesized as simplified structural mimics of the antihypertensive alkaloid tetrandrine (2) and assayed for binding to brain cortical sites labeled with the α1-adrener
