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6-IODO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID is a chemical compound characterized by the molecular formula C8H5IN2O2. It is a derivative of imidazo[1,2-a]pyridine and carboxylic acid, featuring an additional iodine atom attached to the imidazole ring. 6-IODO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID holds potential in pharmaceutical research and drug development due to its possible biological activity, which could be beneficial for medicinal applications. However, it is crucial to handle 6-IODO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID with care and adhere to safety protocols, given the potential hazards associated with iodine-containing substances.

478040-59-4

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478040-59-4 Usage

Uses

Used in Pharmaceutical Research:
6-IODO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID is used as a research compound for exploring its biological activity and potential therapeutic effects. Its unique structure and the presence of an iodine atom may contribute to its pharmacological properties, making it a candidate for further investigation in drug development.
Used in Drug Development:
In the pharmaceutical industry, 6-IODO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID is utilized as a starting material or intermediate in the synthesis of new drugs. Its chemical properties and potential interactions with biological targets could lead to the discovery of novel therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 478040-59-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,0,4 and 0 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 478040-59:
(8*4)+(7*7)+(6*8)+(5*0)+(4*4)+(3*0)+(2*5)+(1*9)=164
164 % 10 = 4
So 478040-59-4 is a valid CAS Registry Number.

478040-59-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names 6-IODO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:478040-59-4 SDS

478040-59-4Downstream Products

478040-59-4Relevant academic research and scientific papers

Synthesis, molecular docking and anti-mycobacterial evaluation of new imidazo[1,2-a]pyridine-2-carboxamide derivatives

Jose, Gilish,Kumara, T.H. Suresha,Nagendrappa, Gopalpur,Sowmya,Sriram, Dharmarajan,Yogeeswari, Perumal,Sridevi, Jonnalagadda Padma,Row, Tayur N. Guru,Hosamani, Amar A.,Sujan Ganapathy,Chandrika,Narendra

, p. 616 - 627 (2015)

New anti-tubercular agents, imidazo[1,2-a]pyridine-2-carboxamide derivatives (5a-q) have been designed and synthesized. The structural considerations of the designed molecules were further supported by the docking study with a long-chain enoyl-acyl carrier protein reductase (InhA). The chemical structures of the new compounds were characterized by IR, 1H NMR, 13C NMR, HRMS and elemental analysis. In addition, single crystal X-ray diffraction has also been recorded for compound 5f. Compounds were evaluated in vitro against Mycobacterium tuberculosis H37Rv, and cytotoxicity against HEK-293T cell line. Amongst the tested compounds 5j, 5l and 5q were emerged as good anti-tubercular agents with low cytotoxicity. The structure-anti TB activity relationship of these derivatives was explained by molecular docking.

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