478081-67-3Relevant academic research and scientific papers
CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF
-
Paragraph 1315, (2018/04/17)
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.
ISOXAZOLE-IMIDAZOLE DERIVATIVES
-
Page/Page column 12, (2009/01/24)
The present invention is concerned isoxazole-imidazole derivatives having affinity and selectivity for GABA A α5 receptor binding site, their manufacture, pharmaceutical compositions containing them and their use for enhancing cognition or for the treatment of cognitive disorders like Alzheimer's disease. In particular, the present invention is concerned with aryl-isoxazol-4-yl-imidazole derivatives of formula I wherein R1, R2 and R3 are as described in the specification.
ISOXAZOLE-PYRIDINE DERIVATIVES
-
Page/Page column 37, (2009/06/27)
The present invention is concerned with isoxazole-pyridine derivatives of formula I wherein X, R1 to R6 are as described herein. The compounds are active on the GABA A α5 receptor binding site and useful for the treatment of cognitive disorders, such as Alzheimer's disease.
