478258-67-2 Usage
Uses
Used in Pharmaceutical Industry:
6-Chloro-N-methyl-2-(methylsulfanyl)-4-pyrimidinamine is used as an intermediate in the synthesis of pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
6-CHLORO-N-METHYL-2-(METHYLSULFANYL)-4-PYRIMIDINAMINE also serves as an intermediate in the synthesis of agrochemicals. It plays a role in the creation of products designed to protect crops and enhance agricultural productivity.
Used as a Herbicide:
6-Chloro-N-methyl-2-(methylsulfanyl)-4-pyrimidinamine has been studied for its potential use as a herbicide. It may contribute to the development of effective weed control solutions that support sustainable farming practices.
Used as a Fungicide:
Additionally, it has been explored for its potential as a fungicide, indicating its possible role in combating fungal infections that can damage crops and other plants.
Used in Materials Science:
6-CHLORO-N-METHYL-2-(METHYLSULFANYL)-4-PYRIMIDINAMINE may also find applications in the development of new materials. Its unique properties could be harnessed to create innovative materials with specific characteristics for various industries.
Used in Organic Synthesis:
6-Chloro-N-methyl-2-(methylsulfanyl)-4-pyrimidinamine is utilized in organic synthesis, where it can be a valuable building block for the creation of a wide range of organic compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 478258-67-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,2,5 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 478258-67:
(8*4)+(7*7)+(6*8)+(5*2)+(4*5)+(3*8)+(2*6)+(1*7)=202
202 % 10 = 2
So 478258-67-2 is a valid CAS Registry Number.
478258-67-2Relevant academic research and scientific papers
Prieur, Vanessa,Pujol, M. Dolors,Guillaumet, Gérald
, p. 6547 - 6556 (2015)
New pyrrolo[2,3-d]pyrimidines that have aryl groups at the 2-, 4-, and 6-positions were prepared by the arylation reaction of 4-chloro-7-methyl-2-(methylthio)-6-phenylpyrrolo[2,3-d]pyrimidine (6) and the corresponding arylboronic acid under Suzuki-Miyaura conditions followed by a second arylation under Liebeskind-Srogl cross-coupling conditions. A parallel study that began with the C-2 chemoselective arylation of 6 under Liebeskind-Srogl conditions followed by a Suzuki-Miyaura coupling at C-4 was carried out, and the results of each route were compared. All of the tranformations were performed under microwave irradiation. Several triarylpyrrolopyrimidines were readily prepared from 4,6-dichloro-2-(methylthio)pyrimidine (2) in excellent yields by using effective cross-coupling reactions. An advantage of this method is its tolerance towards various substituted aryl groups.
Discovery of High-Affinity Inhibitors of the BPTF Bromodomain
Lu, Tian,Lu, Haibo,Duan, Zhe,Wang, Jun,Han, Jie,Xiao, Senhao,Chen, HuanHuan,Jiang, Hao,Chen, Yu,Yang, Feng,Li, Qi,Chen, Dongying,Lin, Jin,Li, Bo,Jiang, Hualiang,Chen, Kaixian,Lu, Wenchao,Lin, Hua,Luo, Cheng
, p. 12075 - 12088 (2021/09/02)
The dysfunctional bromodomain PHD finger transcription factor (BPTF) exerts a pivotal influence in the occurrence and development of many human diseases, particularly cancers. Herein, through the structural decomposition of the reported BPTF inhibitor TP-
