478258-67-2 Usage
General Description
6-Chloro-N-methyl-2-(methylsulfanyl)-4-pyrimidinamine is a chemical compound with the molecular formula C6H8ClN3S. It is a pyrimidine derivative with a chlorine atom at the 6th position and a methylsulfanyl group at the 2nd position of the pyrimidine ring. 6-CHLORO-N-METHYL-2-(METHYLSULFANYL)-4-PYRIMIDINAMINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential use as a herbicide and fungicide. Additionally, it may have applications in the development of new materials and organic synthesis. Overall, 6-Chloro-N-methyl-2-(methylsulfanyl)-4-pyrimidinamine is a versatile compound with various potential uses in the fields of pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 478258-67-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,2,5 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 478258-67:
(8*4)+(7*7)+(6*8)+(5*2)+(4*5)+(3*8)+(2*6)+(1*7)=202
202 % 10 = 2
So 478258-67-2 is a valid CAS Registry Number.
478258-67-2Relevant articles and documents
A Strategy for the Triarylation of Pyrrolopyrimidines by Using Microwave-Promoted Cross-Coupling Reactions
Prieur, Vanessa,Pujol, M. Dolors,Guillaumet, Gérald
, p. 6547 - 6556 (2015)
New pyrrolo[2,3-d]pyrimidines that have aryl groups at the 2-, 4-, and 6-positions were prepared by the arylation reaction of 4-chloro-7-methyl-2-(methylthio)-6-phenylpyrrolo[2,3-d]pyrimidine (6) and the corresponding arylboronic acid under Suzuki-Miyaura conditions followed by a second arylation under Liebeskind-Srogl cross-coupling conditions. A parallel study that began with the C-2 chemoselective arylation of 6 under Liebeskind-Srogl conditions followed by a Suzuki-Miyaura coupling at C-4 was carried out, and the results of each route were compared. All of the tranformations were performed under microwave irradiation. Several triarylpyrrolopyrimidines were readily prepared from 4,6-dichloro-2-(methylthio)pyrimidine (2) in excellent yields by using effective cross-coupling reactions. An advantage of this method is its tolerance towards various substituted aryl groups.
