478259-73-3 Usage
Uses
Used in Pharmaceutical Industry:
TPCA-1 is used as a therapeutic agent for the treatment of inflammatory and autoimmune diseases due to its ability to inhibit IKK-2, a regulator of the NF-κB signaling pathway. This inhibition can help reduce inflammation and modulate immune responses, providing relief from various disease symptoms.
Used in Oncology:
In the field of oncology, TPCA-1 is used as a potential treatment for certain types of cancer. Its inhibition of IKK-2 can disrupt cancer cell survival and proliferation, making it a valuable tool in the fight against cancer.
Used in Drug Discovery and Personalized Medicine:
TPCA-1 is utilized as a research compound in the development of new drugs and personalized medicine approaches. Its selective targeting of IKK-2 allows for the exploration of its potential in treating specific conditions and tailoring treatments to individual patient needs.
Check Digit Verification of cas no
The CAS Registry Mumber 478259-73-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,2,5 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 478259-73:
(8*4)+(7*7)+(6*8)+(5*2)+(4*5)+(3*9)+(2*7)+(1*3)=203
203 % 10 = 3
So 478259-73-3 is a valid CAS Registry Number.
478259-73-3Relevant academic research and scientific papers
HETEROARYL COMPOUNDS USEFUL AS RAF KINASE INHIBITORS
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Page/Page column 74; 75, (2010/08/04)
The present invention provides compounds of formula (I) useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf -mediated diseases.
Heterocyclic Compounds Useful as RAF Kinase Inhibitors
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Page/Page column 50, (2009/01/24)
The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.
COMPOUNDS USEFUL AS RAF KINASE INHIBITORS
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Page/Page column 94, (2009/03/07)
The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.
