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4-p-tolyloxy-pyridine is an organic compound characterized by its chemical formula C12H11NO. It features a pyridine ring, which is a six-membered aromatic ring containing one nitrogen atom, and a 4-methoxyphenyl group (also known as p-tolyloxy) attached to the pyridine at the 4-position. 4-p-tolyloxy-pyridine is a derivative of pyridine, with the methoxy group providing an additional electron-donating effect, which can influence its chemical reactivity and physical properties. It is typically used in the synthesis of various pharmaceuticals and agrochemicals due to its potential to form stable complexes with metal ions. The compound's structure allows for potential applications in medicinal chemistry, particularly in the development of new drugs targeting specific receptors or enzymes.

4783-59-9

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4783-59-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4783-59-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,8 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4783-59:
(6*4)+(5*7)+(4*8)+(3*3)+(2*5)+(1*9)=119
119 % 10 = 9
So 4783-59-9 is a valid CAS Registry Number.

4783-59-9Relevant academic research and scientific papers

HETEROARYL ARYL ETHERS

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Page/Page column 4, (2010/07/10)

The present invention relates to a process for the preparation of optionally substituted heteroaryl aryl ethers, in particular of phenoxypyridines.

Effect of microwave heating on Ullmann-type heterocycle-aryl ether synthesis using chloro-heterocycles

D'Angelo, Noel D.,Peterson, Joseph J.,Booker, Shon K.,Fellows, Ingrid,Dominguez, Celia,Hungate, Randall,Reider, Paul J.,Kim, Tae-Seong

, p. 5045 - 5048 (2007/10/03)

Ullmann ether synthesis was conducted on a variety of chloro-heterocycles with different phenols using optimized conditions involving copper powder and cesium carbonate. On many substrates, microwave heating afforded higher yields in significantly shorter reaction times compared to conventional heating conditions. These findings provide a facile method for aryl ether synthesis from chloropyridines, chloroquinolines, and chlorobenzothiazoles.

Oxamides as novel NR2B selective NMDA receptor antagonists

Barta-Szalai, Gizella,Borza, Istvan,Bozo, Eva,Kiss, Csilla,Agai, Bela,Proszenyak, Agnes,Keseru, Gyoergy M.,Gere, Aniko,Kolok, Sandor,Galgoczy, Kornel,Horvath, Csilla,Farkas, Sandor,Domany, Gyoergy

, p. 3953 - 3956 (2007/10/03)

A novel series of oxamides derived from indole-2-carboxamides was identified as potent NR2B selective NMDA receptor antagonists. Several members of this group showed good analgesic activity in the mouse formalin test.

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