63843-49-2

Usage

Uses

Used in Pharmaceutical Industry:
4-(4-METHYLPHENOXY)PIPERIDINE HYDROCHLORIDE is used as a chemical intermediate for the synthesis of pharmaceutical compounds. Its complex structure allows for the creation of a wide range of drug molecules, making it a valuable component in the development of new medications.
Used in Performance Materials Industry:
4-(4-METHYLPHENOXY)PIPERIDINE HYDROCHLORIDE is used as a building block in the production of performance materials. Its unique structure and properties contribute to the development of materials with enhanced characteristics, such as improved strength, durability, or chemical resistance.
Used in Chemical Research:
4-(4-METHYLPHENOXY)PIPERIDINE HYDROCHLORIDE is used as a research compound in the study of organic chemistry. Its complex structure and reactivity make it an interesting subject for exploring new chemical reactions and understanding the behavior of similar compounds.

InChI:InChI=1/C12H17NO/c1-10-2-4-11(5-3-10)14-12-6-8-13-9-7-12/h2-5,12-13H,6-9H2,1H3

Upstream product

• 5382-16-1 4-HYDROXYPIPERIDINE 
• 624-31-7 4-tolyl iodide 
• 4783-59-9 4-p-tolyloxy-pyridine 
• 106-44-5 p-cresol 
• 626-61-9 4-Chloropyridine 

Downstream Products

• 1223431-72-8 (6-bromopyridin-3-yl)[4-(p-tolyloxy)piperidin-1-yl]methanone 
• 97840-06-7 1-{N-{3-[2-(4-Fluorophenyl)-1,3-dioxolan-2-yl]propyl}-N-methylaminoacetyl}-4-(4-methylphenoxy)piperidine oxalate 
• 496055-13-1 oxo-(4-p-tolyloxy-piperidin-1-yl)-acetic acid 
• 681509-04-6 4-[4-(4-methylphenoxy)piperidin-1-yl]phenol 
• 1026550-74-2 1-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-4-p-tolyloxy-piperidine 
• 496055-12-0 oxo-(4-p-tolyloxy-piperidin-1-yl)-acetic acid ethyl ester 

Relevant academic research and scientific papers

N- versus O-arylation of aminoalcohols: Orthogonal selectivity in copper-based catalysts

Two complementary protocols for copper-catalyzed arylation of aminoalcohols were developed. Selective N-arylation was accomplished at room temperature using 2-isobutyrylcyclohexanone (a β-diketone) as supporting ligand, while selective O-arylation require

Oxamides as novel NR2B selective NMDA receptor antagonists

A novel series of oxamides derived from indole-2-carboxamides was identified as potent NR2B selective NMDA receptor antagonists. Several members of this group showed good analgesic activity in the mouse formalin test.

Piperidylalkylindoles. 1. Hypotensive activity of 3-[2-(phenoxypiperidyl)ethyl]indoles

A series of 3-[2-(phenoxypiperidyl)ethyl]indoles was synthesized and evaluated for hypotensive activity in the spontaneous hypertensive rat. Maximum hypotensive activity appeared when the phenoxy substituent was para substituted and occupied the 4 position of the piperidine ring.

Method of treating pain and hypertension

3-[2-(Phenyloxycycloazalkyl)ethyl]indoles possessing antihypertensive, analgesic, and tranquilizing properties and process for their preparation are described.