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478363-03-0

Boc-Map-Hmp-Gly-N-Me-L-Leu-Gly-N-Me-L-Val-O,N-diMe-L-Tyr-Ibu-N-Me-L-Ala is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 478363-03-0 Structure

  • Basic information

    1. Product Name: Boc-Map-Hmp-Gly-N-Me-L-Leu-Gly-N-Me-L-Val-O,N-diMe-L-Tyr-Ibu-N-Me-L-Ala
    2. Synonyms: Boc-Map-Hmp-Gly-N-Me-L-Leu-Gly-N-Me-L-Val-O,N-diMe-L-Tyr-Ibu-N-Me-L-Ala
    3. CAS NO:478363-03-0
    4. Molecular Formula:
    5. Molecular Weight: 1117.39
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 478363-03-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Boc-Map-Hmp-Gly-N-Me-L-Leu-Gly-N-Me-L-Val-O,N-diMe-L-Tyr-Ibu-N-Me-L-Ala(CAS DataBase Reference)
    10. NIST Chemistry Reference: Boc-Map-Hmp-Gly-N-Me-L-Leu-Gly-N-Me-L-Val-O,N-diMe-L-Tyr-Ibu-N-Me-L-Ala(478363-03-0)
    11. EPA Substance Registry System: Boc-Map-Hmp-Gly-N-Me-L-Leu-Gly-N-Me-L-Val-O,N-diMe-L-Tyr-Ibu-N-Me-L-Ala(478363-03-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 478363-03-0(Hazardous Substances Data)

478363-03-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 478363-03-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,3,6 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 478363-03:
(8*4)+(7*7)+(6*8)+(5*3)+(4*6)+(3*3)+(2*0)+(1*3)=180
180 % 10 = 0
So 478363-03-0 is a valid CAS Registry Number.

478363-03-0Relevant articles and documents

Lyngbyastatin 1 and Ibu-epilyngbyastatin 1: Synthesis, stereochemistry, and NMR line broadening

Bai, Ruoli,Bates, Robert B.,Hamel, Ernest,Moore, Richard E.,Nakkiew, Pichaya,Pettit, George R.,Sufi, Bilal A.

, p. 1824 - 1829 (2007/10/03)

The synthesis of a lyngbyastatin 1-Ibu-epilyngbyastatin 1 mixture combined with NMR and molecular modeling studies proved that natural lyngbyastatin 1 was only one Ibu epimer rather than a mixture of both and that the configuration of this epimer in the Ibu unit was R. The substance isolated with lyngbyastatin 1 was Ibu-epidolastatin 12. The extreme broadness in the proton NMR spectra of lyngbyastatin 1 and Ibu-epidolastatin 12 was exchange broadening due to rotation about the Ibu-Ala amide bond. It was a consequence of (1) a small energy difference between the cis and trans forms of this bond, (2) a substantial difference in conformation between these forms, and (3) a lowered barrier between them compared to most amide bonds (due to steric hindrance). The synthetic lyngbyastatin 1-Ibu-epilyngbyastatin 1 mixture had significant activities against cancer cells and in stimulating actin polymerization, but was less active than dolastatin 11 in all assays.

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