478372-42-8

Basic information

• Product Name: 3-(3-{[(4-Chloro-2-fluorobenzoyl)amino]-methyl}-4-propoxyphenyl)-5-fluorobenzoic acid
• CAS NO: 478372-42-8
• Molecular Weight: 459.877
• Mol File: 478372-42-8.mol

Chemical Properties

• CAS DataBase Reference: 3-(3-{[(4-Chloro-2-fluorobenzoyl)amino]-methyl}-4-propoxyphenyl)-5-fluorobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-{[(4-Chloro-2-fluorobenzoyl)amino]-methyl}-4-propoxyphenyl)-5-fluorobenzoic acid(478372-42-8)
• EPA Substance Registry System: 3-(3-{[(4-Chloro-2-fluorobenzoyl)amino]-methyl}-4-propoxyphenyl)-5-fluorobenzoic acid(478372-42-8)

Safety Data

• Hazardous Substances Data: 478372-42-8(Hazardous Substances Data)

Upstream product

• 446-30-0 4-chloro-2-fluorobenzoic acid 

Relevant articles and documents

CARBOXYLIC ACID DERIVATIVE AND MEDICINE COMPRISING SALT OR ESTER OF THE SAME

The present invention provides novel carboxylic acid derivatives useful as an insulin sensitizer, a salt thereof or a hydrate of them, and a medicament comprising the derivative as the active ingredient. Specifically, it provides a carboxylic acid derivative represented by the following formula: (wherein L represents a single bond, or a C1 to C6 alkylene group, a C2 to C6 alkenylene group or a C2 to C6 alkynylene group, each of which may have one or more substituent groups; M represents a single bond, or a C1 to C6 alkylene group, a C2 to C6 alkenylene group or a C2 to C6 alkynylene group, each of which may have one or more substituent groups; T represents a single bond, or a C1 to C3 alkylene group, a C2 to C3 alkenylene group or a C2 to C3 alkynylene group, each of which may have one or more substituent groups; W represents a carboxyl group; X represents a single bond, an oxygen atom, or a group represented by the various substituent groups including -NRX1CQ1O- (wherein Q1 represents an oxygen atom or a sulfur atom; RX1 represents a hydrogen atom, a cyano group, a formyl group, or various groups including a C1 to C6 alkyl group and a C1 to C6 hydroxyalkyl group, each of which may have one or more substituent groups) , ONRX1CQ1-, -NRX1CQ1-, -CQ1NRX1-, -NRX1aCQ1NRX1b-, -Q2SO2- and -SO2Q2-; Y represents a 5 to 14-membered aromatic group which may have one or more substituent groups and one or more hetero atoms, or a C3 to C7 alicyclic hydrocarbon group; and the rings Z and U may be the same as or different from each other and each represents a 5 to 14-membered aromatic group which may have 1 to 4 substituent groups and one or more hetero atoms, and the ring may be partially saturated.), a salt thereof, an ester thereof or a hydrate of them.