478489-09-7

Basic information

• Product Name: 5-(3-Chloro-thiophen-2-yl)-3-(4-cyano-phenyl)-[1,2,4]-oxadiazole
• CAS NO: 478489-09-7
• Molecular Weight: 287.729
• Mol File: 478489-09-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(3-Chloro-thiophen-2-yl)-3-(4-cyano-phenyl)-[1,2,4]-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-Chloro-thiophen-2-yl)-3-(4-cyano-phenyl)-[1,2,4]-oxadiazole(478489-09-7)
• EPA Substance Registry System: 5-(3-Chloro-thiophen-2-yl)-3-(4-cyano-phenyl)-[1,2,4]-oxadiazole(478489-09-7)

Safety Data

• Hazardous Substances Data: 478489-09-7(Hazardous Substances Data)

Upstream product

• 22179-85-7 4-cyanobenzamidoxime 
• 86427-02-3 3-chlorothiophene-2-carbonyl chloride 

Relevant articles and documents

Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, Ar3, A, B and D are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.