478660-34-3Relevant academic research and scientific papers
Asymmetric Mannich reaction of dicarbonyl compounds with α-amido sulfones catalyzed by cinchona alkaloids and synthesis of chiral dihydropyrimidones
Lou, Sha,Dai, Peng,Schaus, Scott E.
, p. 9998 - 10008 (2008/04/05)
(Chemical Equation Presented) The highly enantioselective cinchona alkaloid-catalyzed Mannich reaction of dicarbonyl compounds with α-amido sulfones as acyl imine precursors is described. The reaction requires 10 mol % of the cinchona alkaloid catalyst, w
CHIRAL AMINE-CATALYZED ASYMMETRIC ADDITION OF CARBON-CENTERED NUCLEOPHILES TO IMINES
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Page/Page column 96, (2010/11/25)
The present invention relates to an asymmetric synthesis useful for preparing compounds useful for the treatment of cardiovascular diseases and for studying the role of motor proteins in cell cycle progression.
