478706-18-2

Upstream product

• 23795-02-0 3-(4-hydroxy-phenyl)-propionic acid ethyl ester 
• 250284-66-3 ethyl 3-(3-bromo-4-hydroxyphenyl)propanoate 
• 61292-90-8 ethyl 3-(4-hydroxy-3-methoxyphenyl)propanoate 
• 478706-17-1 ethyl 3-(4-benzyloxy-3-bromophenyl)propionate 

Downstream Products

• 478706-21-7 3-(4-{2-benzyloxy-5-[3-(2,4-bis-benzyloxyphenyl)-3-oxopropyl]phenoxy}-3-methoxyphenyl)-1-(2,4-bis-benzyloxyphenyl)propan-1-one 
• 351340-16-4 4,2',4',2''',4'''-Pentahydroxy-3''-methoxy-3-O-4''-tetrahydrobichalcone 
• 848476-25-5 3-(4-benzyloxy-3-{4-[3-(2,4-dimethoxy-phenyl)-3-oxo-propyl]-2-methoxy-phenoxy}-phenyl)-1-(2,4-dimethoxy-phenyl)-propan-1-one 
• 478706-20-6 3-(4-{2-benzyloxy-5-[2-(methoxymethylcarbamoyl)ethyl]phenoxy}-3-methoxyphenyl)-N-methoxy-N-methylpropionamide 
• 478706-19-3 3-{4-[2-benzyloxy-5-(2-carboxylethyl)phenoxy]-3-methoxyphenyl}propionic acid 

Relevant academic research and scientific papers

Effects of a verbenachalcone derivative on neurite outgrowth, inhibition of caspase induction and gene expression

A verbenachalcone derivative was synthesized and shown to protect N2a cells from caspase induction caused by serum starvation and to enhance the effect of NGF on neurite outgrowth in PC12 cells. As an initial investigation of the compound's mechanism(s) o

Utilization of a copper-catalyzed diaryl ether synthesis for the preparation of verbenachalcone

2-Hydroxy-2′-methoxydiphenyl ethers were efficiently assembled utilizing a catalytic copper mediated coupling of 2-benzyloxybromobenzene derivatives and 2-methoxyphenol derivatives in the presence of cesium carbonate in pyridine followed by debenzylation.