478798-20-8 Usage
Uses
Used in Pharmaceutical Industry:
[4-(PIPERAZINE-1-CARBONYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure, which includes a phenyl ring and a piperazine moiety, makes it a candidate for the development of new drugs, particularly those targeting the central nervous system or other physiological systems where such structural features are known to be active.
Used in Academic Research:
In the field of academic research, [4-(PIPERAZINE-1-CARBONYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER serves as a subject of study for understanding the chemical properties and reactivity of carbamic acid esters. Researchers may use [4-(PIPERAZINE-1-CARBONYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER to explore its potential in forming new chemical bonds, participating in reactions, or as a model for studying the effects of different functional groups on molecular behavior.
Check Digit Verification of cas no
The CAS Registry Mumber 478798-20-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,7,9 and 8 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 478798-20:
(8*4)+(7*7)+(6*8)+(5*7)+(4*9)+(3*8)+(2*2)+(1*0)=228
228 % 10 = 8
So 478798-20-8 is a valid CAS Registry Number.
478798-20-8Relevant academic research and scientific papers
A modified synthesis of iodoazidoaryl prazosin.
Andrus, Merritt B,Mettath, Sashikumar N,Song, Chun
, p. 8284 - 8286 (2007/10/03)
The antihypertension agent iodoazidoaryl prazosin (IAAP) has been made using a convergent route involving addition of an acylated piperazine 7 to 2-chloroquinazoline 5. IAAP has been shown to function as a multidrug resistance (MDR) reversal agent and bind to P-glycoprotein, a transmembrane transport protein. A study is also reported involving palladium-catalyzed substitution with amine heterocycles. With N,N-bis(2,6-diisopropyl)dihydroimidazolium chloride (10) as the ligand (2 mol %) for palladium(II) acetate (2 mol %) in THF at room temperature, morpholine added to 5 in 81% yield.
