Welcome to LookChem.com Sign In|Join Free

CAS

  • or

478868-68-7

Post Buying Request

478868-68-7 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

478868-68-7 Usage

Description

Ethyl 4-(2,4-dichlorophenyl)-2,4-dioxobutanoate, also known as ethyl 2,4-dichlorophenyl-4-oxobutanoate, is a chemical compound derived from dioxobutanoic acid. It features two chlorophenyl groups and is widely utilized in organic synthesis and pharmaceutical research due to its anti-inflammatory and analgesic properties, positioning it as a promising candidate for the development of novel therapeutic agents.

Uses

Used in Pharmaceutical Research:
Ethyl 4-(2,4-dichlorophenyl)-2,4-dioxobutanoate is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential to exhibit anti-inflammatory and analgesic effects, which are crucial for the treatment of pain and inflammation.
Used in Organic Synthesis:
In the field of organic synthesis, ethyl 4-(2,4-dichlorophenyl)-2,4-dioxobutanoate serves as a versatile building block for the creation of complex organic molecules, contributing to the advancement of chemical research and the development of new materials.

Check Digit Verification of cas no

The CAS Registry Mumber 478868-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,8,6 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 478868-68:
(8*4)+(7*7)+(6*8)+(5*8)+(4*6)+(3*8)+(2*6)+(1*8)=237
237 % 10 = 7
So 478868-68-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H10Cl2O4/c1-2-18-12(17)11(16)6-10(15)8-4-3-7(13)5-9(8)14/h3-5H,2,6H2,1H3

478868-68-7Relevant articles and documents

Novel N-benzylpiperidine derivatives of 5-arylisoxazole-3-carboxamides as anti-Alzheimer's agents

Saeedi, Mina,Felegari, Peyman,Iraji, Aida,Hariri, Roshanak,Rastegari, Arezoo,Mirfazli, S. Sara,Edraki, Najmeh,Firuzi, Omidreza,Mahdavi, Mohammad,Akbarzadeh, Tahmineh

, (2020/11/30)

The complex pathophysiology of Alzheimer's disease (AD) has prompted researchers to develop multitarget-directed molecules to find an effective therapy against the disease. In this context, a novel series of N-(1-benzylpiperidin-4-yl)-5-arylisoxazole-3-ca

Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators

Bi, Fangchao,Song, Di,Zhang, Nan,Liu, Zhiyang,Gu, Xinjie,Hu, Chaoyu,Cai, Xiaokang,Venter, Henrietta,Ma, Shutao

, p. 90 - 103 (2018/10/04)

Antibiotic resistance among clinically significant bacterial pathogens is becoming a prevalent threat to public health, and new antibacterial agents with novel mechanisms of action hence are in an urgent need. Utilizing computational docking method and structure-based optimization strategy, we rationally designed and synthesized two series of isoxazol-3-yl- and isoxazol-5-yl-containing benzamide derivatives that targeted the bacterial cell division protein FtsZ. Evaluation of their activity against a panel of Gram-positive and -negative pathogens revealed that compounds B14 and B16 that possessed the isoxazol-5-yl group showed strong antibacterial activity against various testing strains, including methicillin-resistant Staphylococcus aureus and penicillin-resistant S. aureus. Further molecular biological studies and docking analyses proved that the compound functioned as an effective inhibitor to alter the dynamics of FtsZ self-polymerization via a stimulatory mechanism, which finally terminated the cell division and caused cell death. Taken together, these results could suggest a promising chemotype for development of new FtsZ-targeting bactericidal agent.

Facile, novel and efficient synthesis of new pyrazolo[3,4-b]pyridine products from condensation of pyrazole-5-amine derivatives and activated carbonyl groups

Ghaedi,Bardajee,Mirshokrayi,Mahdavi,Shafiee,Akbarzadeh

, p. 89652 - 89658 (2015/11/10)

An efficient synthesis of novel ethyl-1,3,4-triphenyl-1H-pyrazolo[3,4-b]pyridine-6-carboxylate products has been achieved via condensation of pyrazole-5-amine derivatives and activated carbonyl groups, in refluxing acetic acid. This process has been found to be useful in the preparation of new N-fused heterocycle products in good to excellent yields.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 478868-68-7