478868-71-2

Upstream product

• 57961-48-5 ethyl 4-(3-chlorophenyl)-2,4-dioxobutanoate 
• 99-02-5 3'-Chloroacetophenone 
• 191014-88-7 Ethyl 2-hydroxy-4-(3'-chlorophenyl)-4-oxo-2-butenoate 

Downstream Products

• 1197287-47-0 C₁₆H₂₀ClN₃O₂ 
• 1160731-16-7 C₁₂H₁₀ClN₃O₃ 
• 478869-19-1 7-chloro-3-(3-chloro-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-d]pyrimidine 
• 478869-11-3 3-(3-chloro-phenyl)-2,5-dimethyl-2,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one 
• 478868-94-9 4-amino-5-(3-chloro-phenyl)-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 478868-79-0 5-(3-chloro-phenyl)-1-methyl-4-nitroso-1H-pyrazole-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Novel 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-one derivatives as potential anti-cancer agents

A novel series of 3,5,6-trisubstituted pyrazolo[4,3-d]pyrimidin-7-one derivatives, especially 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-ones were synthesized and evaluated for their in vitro anticancer activities against various human cancer cell line

Synthesis of novel 2,3-substituted-2,4-dihydro-pyrazolo[4,3-d]pyrimidine-5,7-diones

Novel 2,3-substituted-2,4-dihydro-pyrazolo[4,3-d]pyrimidine-5,7-diones were successfully synthesized with moderate to good yields using a new synthetic approach. The structures of the regio-isomers in this series were determined by single crystal X-ray an

3-Aryl pyrazolo[4,3-d]pyrimidine derivatives: Nonpeptide CRF-1 antagonists.

The synthesis of a series of 3-aryl pyrazolo[4,3-d]pyrimidines as potential corticotropin-releasing factor (CRF-1) antagonists is described. The effects of substitution on the aromatic ring, the amino group and the pyrazolo ring on CRF-1 receptor binding