47895-41-0

Basic information

• Product Name: {Nickel(II)-(1,2-bis(diphenylphosphino)ethane)2}⁽²⁺⁾
• CAS NO: 47895-41-0
• Molecular Weight: 855.538
• Mol File: 47895-41-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: {Nickel(II)-(1,2-bis(diphenylphosphino)ethane)2}⁽²⁺⁾(CAS DataBase Reference)
• NIST Chemistry Reference: {Nickel(II)-(1,2-bis(diphenylphosphino)ethane)2}⁽²⁺⁾(47895-41-0)
• EPA Substance Registry System: {Nickel(II)-(1,2-bis(diphenylphosphino)ethane)2}⁽²⁺⁾(47895-41-0)

Safety Data

• Hazardous Substances Data: 47895-41-0(Hazardous Substances Data)

Upstream product

• 86119-84-8 phosphoric acid 
• 25842-03-9 [Ni(1,2-bis(diphenylphosphino)ethane)(N₃)2] 

Downstream Products

• 12125-80-3 ferrocenium 
• 15628-25-8 Ni⁽⁰⁾(1,2-bis(diphenylphosphino)ethane)2 
• 79972-38-6 Ni(1,2-bis(diphenylphosphino)ethane)2⁽¹⁺⁾ 

Relevant articles and documents

Nickel-cysteine binding supported by phosphine chelates

The effect of chelating phosphines was tested on the structure and pH-dependent stability of nickel-cysteine binding. (1,2-Bis(diphenylphosphino) ethane (dppe) and 1,1,1-tris[(diphenylphosphino)methyl]ethane (triphos) were used with three different cysteine derivatives (L-cysteine, Cys; L-cysteine ethyl ester, CysEt; cystamine, CysAm) to prepare complexes of the form (dppe)NiCysRn+ and (triphos)NiCysRn+ (n = 0 for Cys; n = 1 for CysEt and CysAm). Similar 31P {1H} NMR spectra for all (dppe)NiCysRn+ confirmed their square-planar P2NiSN coordination spheres. The structure of [(dppe)NiCysAm]PF6 was also confirmed by single-crystal X-ray diffraction methods. The (triphos)- NiCysAm+ and (triphos)NiCysEt+ complexes were fluxional at room temperature by 31P NMR. Upon cooling to -80°C, all gave spectra consistent with a P2NiSN coordination sphere with the third phosphorus uncoordinated. Temperature-dependent 31P NMR spectra showed that a trans P-Ni-S π interaction controlled the scrambling of the coordinated triphos. In aqueous media, (dppe)NiCys was protonated at pH ～ 4-5, leading to possible formation of a nickel-cysteinethiol and eventual cysteine loss at pH - = hydrotris(3,5-dimethylpyrazolyl)borate. Importantly, results with these heterogeneous systems demonstrated the selectivity of these nickel centers for cysteine over methionine and serine and most specifically for N-terminus cysteine. The role of Ni-S π bonding in nickel-cysteine geometries will be discussed, including how these results suggest a mechanism for the movement of electron density from nickel onto the backbone of coordinated cysteine.