478958-05-3

Basic information

• Product Name: 4-{1-[4-(propane-2-sulfinyl)-phenyl]-ethylidene}-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester
• CAS NO: 478958-05-3
• Molecular Weight: 460.681
• Mol File: 478958-05-3.mol

Chemical Properties

• CAS DataBase Reference: 4-{1-[4-(propane-2-sulfinyl)-phenyl]-ethylidene}-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{1-[4-(propane-2-sulfinyl)-phenyl]-ethylidene}-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester(478958-05-3)
• EPA Substance Registry System: 4-{1-[4-(propane-2-sulfinyl)-phenyl]-ethylidene}-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester(478958-05-3)

Safety Data

• Hazardous Substances Data: 478958-05-3(Hazardous Substances Data)

Upstream product

• 478958-03-1 4-(4-isopropylsulfanyl-benzoyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 478958-04-2 4-[1-(4-isopropylsulfanyl-phenyl)-ethylidene]-piperidine 
• 25519-78-2 4-(4-fluorobenzoyl)piperidine hydrochloride 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 478958-13-3 4-[1-(4-isopropylsulfanyl-phenyl)-ethylidene]-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester 

Downstream Products

• 511296-58-5 4-{1-[4-(propane-2-sulfinyl)-phenyl]-ethylidene}-[1,4']bipiperidinyl 

Relevant articles and documents

Improving the oral efficacy of CNS drug candidates: Discovery of highly orally efficacious piperidinyl piperidine M2 muscarinic receptor antagonists

In search of a backup M2 muscarinic receptor antagonist to the previously reported compound 1, we discovered compound (+)-14, which showed superior oral efficacy in animal models. The improvement of oral efficacy was achieved by modulating both