479198-89-5

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 479198-85-1 [5-(2-{2-[5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-1-hydroxy-ethyl}-3-dimethylsulfamoyl-3H-benzoimidazol-5-yl)-thiazol-2-yl]-methyl-carbamic acid tert-butyl ester 
• 479198-83-9 6-(2-N-tert-butoxycarbonyl-N-methyl-aminothiazol-5-yl)-1-(N,N-dimethylsulfamoyl)-benzimidazole 
• 135821-12-4 5-O-<(tert-butyl)diphenylsilyl>-2-deoxy-3,4-O-isopropylidene-aldehydo-D-ribose 

Downstream Products

• 479198-98-6 [5-(2-{5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3-dimethylsulfamoyl-3H-benzoimidazol-5-yl)-thiazol-2-yl]-methyl-carbamic acid tert-butyl ester 
• 479198-92-0 (5-{2-[5-(tert-butyl-diphenyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-3-dimethylsulfamoyl-3H-benzoimidazol-5-yl}-thiazol-2-yl)-methyl-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis, incorporation into triplex-forming oligonucleotide, and binding properties of a novel 2'-deoxy-C-nucleoside featuring a 6-(thiazolyl-5)benzimidazole nucleobase.

[reaction: see text] 6-(Thiazolyl-5)benzimidazole (B(t)()) was designed as a novel nucleobase for the specific recognition of an inverted A.T base pair in a triple helix motif. It was successfully incorporated into an 18-mer triplex-forming oligonucleotid