479258-11-2

Upstream product

• 133332-31-7 (E)-3-(3-cyclopentyloxy-4-methoxyphenyl)-2-propenoic acid 
• 162544-53-8 (E)-3-(3-Cyclopentyloxy-4-methoxy-phenyl)-acryloyl chloride 
• 621-59-0 isovanillin 
• 479258-10-1 (E)-1-[3-(3-cyclopentyloxy-4-methoxyphenyl)-2-propenoyl]-3,5-dimethyl-pyrazole 
• 75-52-5 nitromethane 
• 67387-76-2 3-cyclopentyloxy-4-methoxybenzylaldehyde 
• 137-43-9 Cyclopentyl bromide 

Downstream Products

• 85416-75-7 (R)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one 

Relevant academic research and scientific papers

Enantioselective Michael additions of nitromethane by a catalytic double activation method using chiral Lewis acid and achiral amine catalysts

Reactions of nitromethane with 1-(2-alkenoyl)-3,5-dimethylpyrazoles can be effectively catalyzed by R,R-DBFOX/Ph·Ni(ClO4)2·3H2O and achiral amine bases, each in a catalytic loading of 10 mol %, to give 1-(3-substituted 4-n