479482-38-7

Usage

Uses

Used in Pharmaceutical Industry:
6-Chloro-4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-Dioxide is used as an intermediate in the synthesis of hydroxythienothiazine carboxamides. These compounds are known for their anti-inflammatory, analgesic, and antirheumatic properties, making them valuable in the development of medications to treat various conditions related to inflammation, pain, and rheumatism.

Upstream product

• 70415-50-8 methyl 6-chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylate 1,1-dioxide 
• 7305-71-7 5-methyl-2-thiazol-2-amine 

Relevant academic research and scientific papers

4-Hydroxy-2H-thieno[2,3-e]-1,2-thiazin-3-carboxamide-1,1-dioxides, process for their preparation and pharmaceutical compositions containing them

6-(Halo or trifluoromethyl)-4-hydroxy-N-(5-substituted 2-thiazolyl)-2H-thieno-(2,3-e)-1,2-thiazine-3-carboxamide-1,1-dioxides (I) are new. 6-(Halo or trifluoromethyl)-4-hydroxy-N-(5-substituted 2-thiazolyl)-2H-thieno-(2,3-e)-1,2-thiazine-3-carboxamide-1,1-dioxides of formula (I) and their salts with inorganic or organic bases are new. X = F, Cl, Br or CF3; R1 = H, Me or Et; and R2 = Me or Et. An Independent claim is also included for the preparation of (I).

Thienothiazine compound having anti-inflammatory and analgesic properties and method of making and using the same

The present invention is related to a type of thienothiazine compounds having molecular structure of formula (1) and their pharmaceutically acceptable salts or solvates. The present invention is also related to the method of producing the formula (1) compound, an anti-inflammatory and analgesic pharmaceutical composition containing the formula (1) compound, and the method of using the formula (1) compound to prepare anti-inflammatory and analgesic medicine.