479485-75-1Relevant academic research and scientific papers
Synthesis and reactivity of 1,2-dioxolanes from β,γ-epoxy ketones
Kandur, Wynne V.,Richert, Kathleen J.,Rieder, Curtis J.,Thomas, Andrew M.,Hu, Chunhua,Ziller, Joseph W.,Woerpel
supporting information, p. 2650 - 2653 (2014/06/09)
Five-membered ring peroxides were prepared in one step in 31-86% yield from readily accessible β,γ-epoxy ketones and H2O2. The reaction proceeded via a tetrahydrofuran, which was converted to the thermodynamically favored 1,2-dioxola
Stereoselective Aldol-Type Cyclization Reaction Mediated by Dibutylboron Triflate/Diisopropylethylamine
Das, Sanjib,Li, Lian-Sheng,Sinha, Subhash C.
, p. 123 - 126 (2007/10/03)
(Equation presented) Dibutylboron triflate/diisopropylethylamine mediated aldol-type cyclization provides an expedient route for the stereoselective synthesis of cyclic ethers in a single step. The method is highly efficient for the stereoselective synthe
Scandium-catalyzed allylboration of aldehydes as a practical method for highly diastereo- and enantioselective construction of homoallylic alcohols
Lachance, Hugo,Lu, Xiaosong,Gravel, Michel,Hall, Dennis G.
, p. 10160 - 10161 (2007/10/03)
A general approach for the allylation of aldehydes using stable, air-tolerant camphor-based chiral allylboronates under Sc(OTf)3 catalysis is described. This practical methodology provides both syn and anti propionate units and other homoallylic alcohols with very high levels of diastereo- and enantioselectivity for several substrates, including functionalized aliphatic aldehydes useful toward the elaboration of complex natural products. Copyright
Diastereoselective construction of cis 2,6-disubstituted tetrahydropyran rings via In(OTf)3-catalyzed intramolecular 2,5-oxonium-ene cyclization: Synthetic studies towards the total synthesis of zampanolide and dactylolide
Loh, Teck-Peng,Yang, Jian-Ying,Feng, Li-Chun,Zhou, Yan
, p. 7193 - 7196 (2007/10/03)
Diastereoselective construction of 2,6-disubstituted tetrahydropyrans with an exocyclic double bond was achieved via the In(OTf)3-catalyzed intramolecular 2,5-oxonium-ene cyclization. Its application was further demonstrated by the synthesis of
