479549-24-1

Upstream product

• 479549-19-4 (1R,2R,4R,5R,1'S,2'R,5'S)-4-hydroxy-5-phenylselanyl-cyclohexane-1,2-dicarboxylic acid bis(2'-isopropyl-5'-methyl-cyclohexyl) ester 
• 124-63-0 methanesulfonyl chloride 
• 479549-21-8 (1R,2R,3Z,5R,1'S,2'R,5'S)-5-hydroxy-cyclohex-3-ene-1,2-dicarboxylic acid bis(2'-isopropyl-5'-methyl-cyclohexyl) ester 
• 120143-40-0 (2Z,1'S,2'R,5'S)-but-2-enedioic acid bis(2'-isopropyl-5'methyl-cyclohexyl) ester 
• 73627-88-0 (1R,2R,1'S,2'R,5'S)-cyclohex-4-ene-1,2-dicarboxylic acid bis(2'-isopropyl-5'-methyl-cyclohexyl) ester 
• 86287-64-1 (2E,1'S,2'R,5'S)-but-2-enedioic acid bis(2'-isopropyl-5'methyl-cyclohexyl) ester 
• 15356-60-2 (1S,2R,5S)-(+)-menthol 

Downstream Products

• 479549-29-6 (1R,2Z,6R)-cyclohex-3-ene-1,2-dicarbaldehyde 
• 479549-16-1 (1Z,3R,4R,1'E)-3,4-bis(2'-iodo-vinyl)-cyclohexene 
• 618093-66-6 C₄₄H₆₄N₂O₈Si₂ 
• 220422-37-7 epi,epi-(3''S,4''S)-polycephalin C 
• 15679-28-4 ((1R,6R)-6-(hydroxymethyl)cyclohex-3-enyl)methanol 
• 478703-63-8 (1R,2Z,6R)-(6-hydroxymethyl-cyclohex-2-enyl)methanol 

Relevant academic research and scientific papers

Total synthesis of the polyenoyltetramic acid polycephalin C

The total synthesis of the polyenoyltetramic acid polycephalin C is described. Key steps of the synthesis include a double Swern oxidation, double Takai reaction and a double Stille reaction. In addition, the absolute stereochemistry of the ring junction

Total synthesis of polycephalin C and determination of the absolute configurations at the 3′′,4′′ ring junction

Only through total synthesis could the absolute configuration of the 3′′R,4′′R ring junction of the polyenoltetramic acid polycephalin C (1) be unambiguously established. Key features of the synthesis include a double Swern oxidation, double Stille coupli