480423-17-4

Basic information

• Product Name: N-Tosyl-4-bromo-2-iodo-7-azaindole
• Synonyms: N-Tosyl-4-bromo-2-iodo-7-azaindole;4-Bromo-2-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine;4-Bromo-2-iodo-N-tosyl-7-azaindole;1H-Pyrrolo[2,3-b]pyridine, 4-broMo-2-iodo-1-[(4-Methylphenyl)sulfonyl]-;4-bromo-2-iodo-1-tosyl-7-azaindole;4-Bromo-2-iodo-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine
• CAS NO: 480423-17-4
• Molecular Formula: C₁₄H₁₀BrIN₂O₂S
• Molecular Weight: 477.115
• Mol File: 480423-17-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 574.6°C at 760 mmHg
• Flash Point: 301.3°C
• Appearance: /
• Density: 2g/cm³
• Vapor Pressure: 3.31E-13mmHg at 25°C
• Refractive Index: 1.743
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: N-Tosyl-4-bromo-2-iodo-7-azaindole(CAS DataBase Reference)
• NIST Chemistry Reference: N-Tosyl-4-bromo-2-iodo-7-azaindole(480423-17-4)
• EPA Substance Registry System: N-Tosyl-4-bromo-2-iodo-7-azaindole(480423-17-4)

Safety Data

• Hazardous Substances Data: 480423-17-4(Hazardous Substances Data)

Usage

General Description

N-Tosyl-4-bromo-2-iodo-7-azaindole is a chemical compound with the molecular formula C13H9BrIN2O2S. It is a substituted azaindole derivative with a tosyl group attached to the nitrogen atom. Azaindoles are known for their biological activity, and this compound may have potential applications in pharmaceutical research and drug development. The presence of bromine and iodine atoms in the molecule also adds to its potential utility in organic synthesis and as a building block for creating more complex chemical structures. Its specific properties and potential uses would depend on further research and testing.

InChI:InChI=1/C14H10BrIN2O2S/c1-9-2-4-10(5-3-9)21(19,20)18-13(16)8-11-12(15)6-7-17-14(11)18/h2-8H,1H3

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 348640-06-2 4-bromo-7-azaindole 
• 348640-07-3 4-bromo-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1030610-61-7 [(4-{4-bromo-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-2-yl}phenyl)methyl]dimethylamine 
• 1089669-37-3 1,1-dimethylethyl 5-[1-[(4-methylphenyl)sulfonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,4-dihydro-1(2H)-pyridinecarboxylate 

Relevant articles and documents

Development of Potent PfCLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials

The protein kinase PfCLK3 plays a critical role in the regulation of malarial parasite RNA splicing and is essential for the survival of blood stage Plasmodium falciparum. We recently validated PfCLK3 as a drug target in malaria that offers prophylactic,

General methods for the synthesis and late-stage diversification of 2,4-substituted 7-azaindoles

As part of a medicinal chemistry program, we adapted known synthetic methods for the late-stage diversification of 2,4-substituted 7-azaindoles. The strengths and weaknesses of these strategies are discussed. In the course of this work, three optimized co

PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS

Disclosed are compounds of Formula (IIa), wherein R1, R2, R3A, R3B, R3C, R3D, R3E, and R4 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (IIa)