348640-06-2Relevant articles and documents
OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF
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Paragraph 0592, (2017/03/14)
The present disclosure relates to oxadiazine compounds, pharmaceutical compositions comprising an effective amount of an oxadiazine compound and methods for using an oxadiazine compound in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of an oxadiazine compound.
Solution-phase parallel synthesis of ruxolitinib-derived Janus kinase inhibitors via copper-catalyzed azide-alkyne cycloaddition
Gehringer, Matthias,Forster, Michael,Laufer, Stefan A.
supporting information, p. 5 - 10 (2015/01/30)
A solution-phase parallel synthesis of triazole-derived ruxolitinib analogues was developed in the current study. The method employs copper-catalyzed azide-alkyne cycloaddition to build up the central triazole template. Product isolation by precipitation
CHEMICAL COMPOUNDS
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Page/Page column 23, (2012/01/03)
There is provided pyrimidinyl compounds of Formula (I), wherein: R2 is or pharmaceutically acceptable salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.