4809-95-4

Upstream product

• 21473-01-8 2-naphthalenylmagnesium bromide 
• 109-94-4 formic acid ethyl ester 
• 66-99-9 β-naphthaldehyde 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 613-56-9 Bis(2-naphthyl)ketone 
• 580-13-2 2-bromonaphthalene 

Downstream Products

• 1355718-58-9 (dinaphthalen-2-ylmethyl)triphenylphosphonium bromide 
• 1116086-41-9 di(2-naphthyl)methyl (R)-2-phenylpropanoate 
• 7782-24-3 (S)-2-Phenylpropionic acid 
• 7782-26-5 (R)-2-Phenylpropionic acid 

Relevant academic research and scientific papers

Co(III)-Catalyzed Synthesis of Quinazolines via C-H Activation of N-Sulfinylimines and Benzimidates

C-H activation of arenes has been established as an important strategy for heterocycle synthesis via annulations between arenes and unsaturated coupling partners. However, nitriles failed to act as such a coupling partner. Dioxazolones have been employed as a synthon of nitriles, and subsequent coupling with arenes such as N-sulfinylimines and benzimidates bearing a functionalizable directing group provided facile access to two classes of quinazolines under Co(III)-catalysis.

Facile preparation of aromatic esters from aromatic bromides with ethyl formate or DMF and molecular iodine via aryllithium

Various aromatic bromides were treated with n-BuLi and subsequently with ethyl formate, followed by the reaction with ethanol and molecular iodine in the presence of K2CO3 to provide the corresponding aromatic ethyl esters in good yields. Moreover, aromatic bromides could be transformed into the corresponding aromatic methyl esters in good yields by the treatment with n-BuLi and subsequently with DMF, followed by the reaction with methanol, molecular iodine, and K2CO3. Some aromatics could be also converted into the corresponding aromatic esters in good yields by the treatment with n-BuLi, and subsequently with ethyl formate or DMF, followed by the reaction with molecular iodine and K2CO3. The present reactions offer a novel route for the transition-metal-free, carbon-monoxide-free, and therefore environmentally benign one-pot conversion of aromatic bromides and aromatics into aromatic esters.

Clathrate Formers with Allene Structure - Host Compounds, Crystal Inclusion and Structure of a Dioxane Clathrate

The tetraaryl-substituted allenes 1-8 are synthesized, and their properties in crystal inclusion are determined.Dependent on the type and number of the substituents, host compounds result, which have different inclusion properties and clathrate selectivities.Host 1h forms inclusion compounds with a wide range of apolar and relatively polar cyclic guest solvents (26 inclusions altogether), while 2, 4, 5, and 7b form only one or two inclusions.In two-component solvent systems, high inclusion selectivities are found for the host compounds.The crystal structure of the4*dioxane (1:1) clathrate is reported.Relations between structure and inclusion selectivity are discussed.