481-46-9

Basic information

• Product Name: GINKGETIN
• Synonyms: GINKGETIN;4',5,5'',7-Tetrahydroxy-4''',7''-dimethoxy-8,3'''-biflavone;5,7-Dihydroxy-8-[2-methoxy-5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)phenyl]-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;GINKGETIN(RG)(PLEASE CALL);4H-1-Benzopyran-4-one,5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-;Ginkgetin, 98%, from Ginkgo biloba L.
• CAS NO: 481-46-9
• Molecular Formula: C₃₂H₂₂O₁₀
• Molecular Weight: 566.51108
• Mol File: 481-46-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 297 °C(Solv: acetone (67-64-1))
• Boiling Point: 863.7 °C at 760 mmHg
• Flash Point: 287.1 °C
• Appearance: /
• Density: 1.506 g/cm³
• Vapor Pressure: 2.28E-31mmHg at 25°C
• Refractive Index: 1.714
• PKA: 6.18±0.40(Predicted)
• CAS DataBase Reference: GINKGETIN(CAS DataBase Reference)
• NIST Chemistry Reference: GINKGETIN(481-46-9)
• EPA Substance Registry System: GINKGETIN(481-46-9)

Safety Data

• Hazardous Substances Data: 481-46-9(Hazardous Substances Data)

Usage

Definition

ChEBI: A biflavonoid that is the 7,4'-dimethyl ether derivative of amentoflavone. Isolated from Ginkgo biloba and Dioon, it exhibits anti-HSV-1, antineoplastic and inhibitory activities towards arachidonate 5-lipoxygenase and cyclooxyge ase 2.

InChI:InChI=1/C32H22O10/c1-39-18-10-20(34)30-23(37)13-27(41-28(30)11-18)16-5-8-25(40-2)19(9-16)29-21(35)12-22(36)31-24(38)14-26(42-32(29)31)15-3-6-17(33)7-4-15/h3-14,33-36H,1-2H3

Upstream product

• 3754-52-7 3'-iodo-5,7,4'-trimethoxyflavone 
• 135159-04-5 8-[5-(5,7-Dimethoxy-4-oxo-4H-chromen-2-yl)-2-methoxy-phenyl]-5,7-diisopropoxy-2-(4-isopropoxy-phenyl)-chromen-4-one 

Downstream Products

• 19825-44-6 tetraacetyl from ginkgetin 
• 7507-89-3 2,6-dihydroxy-4-methoxy-acetophenone 
• 88856-57-9 8-(5-acetyl-2-methoxy-phenyl)-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one 
• 99-93-4 4-Hydroxyacetophenone 

Relevant articles and documents

A new strategy for the synthesis of biflavonoids via arylboronic acids

Amentoflavone derivatives were prepared by catalytic coupling of 8-flavone-boronic acids with iodoflavones. 3-Arylflavones, as biflavonoid synthon, are accessible by the method.