7507-89-3

Basic information

• Product Name: 1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE
• Synonyms: 1-(2,6-Dihydroxy-4-methoxyphenyl)ethanone , Tech.;4-O-Methylphloroacetophenone;NSC 401443;4-O-Methylphloracetophenone;Acetophenone, 2',6'-dihydroxy-4'-methoxy-;Ethanone, 1-(2,6-dihydroxy-4-methoxyphenyl)-;2',6'-DIHYDROXY-4'-METHOXYACETOPHENONE;1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE
• CAS NO: 7507-89-3
• Molecular Formula: C₉H₁₀O₄
• Molecular Weight: 182.17
• Product Categories: Aromatic Acetophenones & Derivatives (substituted)
• Mol File: 7507-89-3.mol
• Article Data: 24

Chemical Properties

• Melting Point: 144 °C
• Boiling Point: 356.7 °C at 760 mmHg
• Flash Point: 146.3 °C
• Appearance: /
• Density: 1.284 g/cm³
• PKA: 9.27±0.15(Predicted)
• CAS DataBase Reference: 1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE(7507-89-3)
• EPA Substance Registry System: 1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE(7507-89-3)

Safety Data

• Hazardous Substances Data: 7507-89-3(Hazardous Substances Data)

Usage

Preparation

Obtained by reaction of boiling aqueous potassium hydroxide, ? on the Methyl 3-acetyl-2,4-dihydroxy-6-methoxybenzoate (quantitative yield) ; ? on the 3-trichloroacetyl-2,6-dihydroxy-4-methoxyacetophenone.

Upstream product

• 186581-53-3 diazomethane 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 832-58-6 1-(2,4,6-trimethoxyphenyl)ethanone 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 481-46-9 ginkgetin 
• 249278-28-2 2,4,6-trihydroxyacetophenone monohydrate 
• 2174-64-3 5-methoxyresorcinol 
• 75-36-5 acetyl chloride 
• 108-73-6 3,5-dihydroxyphenol 
• 720698-36-2 2,2,2-trichloro-1-(2,4-dihydroxy-6-methoxy-phenyl)-ethanone 
• 10378-90-2 2,4-dihydroxy-6-methoxy-benzoic acid methyl ester 
• 77-78-1 dimethyl sulfate 
• 521-34-6 sciadopitysin 

Downstream Products

• 136258-09-8 2'-hydroxy-4'-methoxy-6'-tetrahydropyranyloxyacetophenone 
• 136258-10-1 2',6'-dihydroxy-4'-methoxy-3'-tetrahydropyranylacetophenone 
• 76554-79-5 1-(2-ethoxy-6-hydroxy-4-methoxy-phenyl)-ethanone 
• 66568-98-7 5,4'‐dihydroxy‐7,3'‐dimethoxyflavanone 
• 186693-85-6 1-[2-hydroxy-4-methoxy-6-(methoxymethoxy)phenyl]ethan-1-one 
• 62252-12-4 5-hydroxy-3',4',5',7-tetramethoxy-8-prenylflavanone 
• 78983-47-8 2,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4-chromanon 
• 72247-81-5 (+/-) helichromanochalkone 
• 78983-48-9 2-(4-benzyloxyphenyl)-2,5-dihydroxy-7-methoxy-4-chromanon 
• 14218-45-2 <2-Acetyl-3-hydroxy-5-methoxy-phenoxy>-essigsaeure 
• 1013913-57-9 1-{2,6-dihydroxy-4-methoxy-3-[(1R,6R)-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-yl]phenyl}ethanone 
• 53771-29-2 3.5-Diallylphloroacetophenon 
• 1417701-56-4 1,1'-(methylenebis(2,6-dihydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)-3,1-phenylene))bis(ethan-1-one) 
• 98569-63-2 1,1'-(methylenebis(2,6-dihydroxy-4-methoxy-5-methyl-3,1-phenylene))bis(ethan-1-one) 

Relevant articles and documents

Structure of pleoside from Pleopeltis thunbergiana]

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Structural elucidation, total synthesis, and cytotoxic activity of effphenol A

A highly substituted phenol derivative, effphenol A (1), was isolated from the deep-sea-derived fungus Trichobotrys effuse FS524. Its complete structural assignment was established through a combination of spectroscopic analysis together with single-crystal X-ray diffraction experiments and further unequivocally confirmed by a biomimetic total synthesis. Structurally, effphenol A possesses a poly-substituted 6-5/6/6 tetracyclic ring system, which represents the first case of such a skeleton found in nature. Furthermore, the cytotoxic activity of effphenol A (1) toward four human cancer cell lines was assayed. This journal is

Structural features and antioxidant activities of Chinese quince (Chaenomeles sinensis) fruits lignin during auto-catalyzed ethanol organosolv pretreatment

Chinese quince fruits (Chaenomeles sinensis) have an abundance of lignins with antioxidant activities. To facilitate the utilization of Chinese quince fruits, lignin was isolated from it by auto-catalyzed ethanol organosolv pretreatment. The effects of three processing conditions (temperature, time, and ethanol concentration) on yield, structural features and antioxidant activities of the auto-catalyzed ethanol organosolv lignin samples were assessed individually. Results showed the pretreatment temperature was the most significant factor; it affected the molecular weight, S/G ratio, number of β-O-4′ linkages, thermal stability, and antioxidant activities of lignin samples. According to the GPC analyses, the molecular weight of lignin samples had a negative correlation with pretreatment temperature. 2D-HSQC NMR and Py-GC/MS results revealed that the S/G ratios of lignin samples increased with temperature, while total phenolic hydroxyl content of lignin samples decreased. The structural characterization clearly indicated that the various pretreatment conditions affected the structures of organosolv lignin, which further resulted in differences in the antioxidant activities of the lignin samples. These results can be helpful for controlling and optimizing delignification during auto-catalyzed ethanol organosolv pretreatment, and they provide theoretical support for the potential applications of Chinese quince fruits lignin as a natural antioxidant in the food industry.