481014-74-8Relevant academic research and scientific papers
Unified approach to substituted allenoates via Pd-catalyzed β-hydride elimination of (E)-enol triflates
El Arba, Marie,Dibrell, Sara E.,Crouch, Ian T.,Frantz, Doug E.
supporting information, p. 5446 - 5449 (2017/11/06)
A robust synthesis of allenoates via a Pdcatalyzed β-hydride elimination of (E)-enol triflates is presented. Salient features of this method include low catalyst loadings, mild reaction conditions, and the ability to access all four patterns of substituted allenoates from a single substrate class.
Pd-catalyzed asymmetric β-hydride elimination en route to chiral allenes
Crouch, Ian T.,Neff, Robynne K.,Frantz, Doug E.
, p. 4970 - 4973 (2013/06/04)
We wish to report our preliminary results on the discovery and development of a catalytic, asymmetric β-hydride elimination from vinyl Pd(II)-complexes derived from enol triflates to access chiral allenes. To achieve this, we developed a class of chiral p
