57594-17-9

Basic information

• Product Name: benzyl 5-methyl-3-oxohexanoate
• Synonyms: benzyl 5-methyl-3-oxohexanoate
• CAS NO: 57594-17-9
• Molecular Weight: 234.295
• Mol File: 57594-17-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl 5-methyl-3-oxohexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 5-methyl-3-oxohexanoate(57594-17-9)
• EPA Substance Registry System: benzyl 5-methyl-3-oxohexanoate(57594-17-9)

Safety Data

• Hazardous Substances Data: 57594-17-9(Hazardous Substances Data)

Upstream product

• 146380-12-3 5-(1-hydroxy-3-methylbutylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 100-51-6 benzyl alcohol 
• 34036-16-3 5-methyl-3-oxo-hexanoic acid ethyl ester 
• 481014-74-8 (+/-)-benzyl 5-methyl-hexa-2,3-dienoate 
• 5396-89-4 benzyl acetoacetate 
• 108-12-3 isopentanoyl chloride 
• 57594-18-0 Benzyl-α-isovalerylacetoacetat 

Downstream Products

• 1026105-88-3 benzyl 2-diazo-5-methyl-3-oxohexanoate 
• 1026105-91-8 benzyl 2-hydroxy-5-methyl-3-oxohexanoate 
• 1026105-93-0 benzyl-5-isobutyl-2-oxo-1,3-dioxole-4-carboxylate 
• 481014-74-8 (R)-(-)-benzyl 5-methylhexa-2,3-dienoate 
• 481014-74-8 (S)-(-)-benzyl 5-methylhexa-2,3-dienoate 
• 1427662-81-4 (E)-benzyl 5-methyl-3-(((trifluoromethyl)sulfonyl)oxy)hex-2-enoate 
• 1026862-50-9 2-[1-Dimethylamino-meth-(Z)-ylidene]-5-methyl-3-oxo-hexanoic acid benzyl ester 

Relevant articles and documents

Oxone-promoted hydration of electron-deficient allenic esters and ketones into 1,3-dicarbonyl compounds

Abstract A novel and mild protocol for the hydration of electron-deficient allenic esters and ketones into various 1,3-dicarbonyl compounds is described. The hydration of allenes promoted by oxone in DMF afforded the corresponding products in moderate to good yields. This work features the employment of only a catalytic amount of inexpensive and nontoxic solid reagent oxone (2KHSO5·KHSO4·K2SO4), avoiding the utility of toxic metals or traditional Br?nsted acids, in a green version of viewpoint. A possible reaction mechanism for this transformation is also primarily proposed.

Microwave-assisted solution-phase synthesis of 1,4,5-trisubstituted pyrazoles

A small parallel library of 1,4,5-trisubstituted pyrazoles was prepared in solution using a three-step procedure starting from Meldrum acid. The Meldrum acid was acylated with different acyl chlorides and the products opened with different alcohols and amines to give substituted β-keto esters and β-keto amines. Further reaction with N,N-dimethylformamide dimethylacetal and the final cyclisation were effectively carried out under microwave irradiation. Scavenger resins were employed exclusively in the first step, whereas use of microwaves allowed complete conversion of the starting materials in the other two steps. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.