481048-35-5Relevant academic research and scientific papers
New syntheses of E7389 C14-C35 and halichondrin C14-C38 building blocks: Double-inversion approach
Kim, Dae-Shik,Dong, Cheng-Guo,Kim, Joseph T.,Guo, Haibing,Huang, Jian,Tiseni, Paolo S.,Kishi, Yoshito
supporting information; scheme or table, p. 15636 - 15641 (2010/01/30)
With sequential use of catalytic asymmetric Cr-mediated coupling reactions, E7389 C14-C35 and halichondrin C14-C38 building blocks have been stereoselectively synthesized. The C19-C20 bond is first formed via the catalytic asymmetric Ni/Cr-mediated coupli
Further improvement on sulfonamide-based ligand for catalytic asymmetric 2-haloallylation and allylation
Zhang, Zhiyu,Huang, Jian,Ma, Bin,Kishi, Yoshito
supporting information; experimental part, p. 3073 - 3076 (2009/05/11)
(Chemical Equation Presented) The sulfonamide-based ligand B was found to exhibit an outstanding crystallinity and perform well as a ligand for Cr-mediated catalytic asymmetric 2-haloallylation and allylation. The new ligand has an appealing advantage ove
Fe/Cr- and Co/Cr-mediated catalytic asymmetric 2-haloallylations of aldehydes
Kurosu, Michio,Lin, Mei-Huey,Kishi, Yoshito
, p. 12248 - 12249 (2007/10/03)
The first example to couple aldehydes and 3-bromo-2-halopropenes in a catalytic asymmetric manner is reported. The coupling reaction is effected by the use of a chiral sulfonamide-Cr complex (prepared in situ from 1d, CrBr3, Fe(III) or from Co(II), Et3N, and Mn), TMSCl, and 2,6-lutidine. The method reported here is operationally simple and scalable, furnishing 3-halohomoallylic alcohols with a synthetically useful level of enantiomeric excess. Copyright
New catalytic cycle for couplings of aldehydes with organochromium reagents
Namba, Kosuke,Kishi, Yoshito
, p. 5031 - 5033 (2007/10/03)
(Chemical Equation Presented) A new catalytic cycle has been developed to effect all three subgroups of Cr-mediated couplings, i.e., (1) Ni/Cr-mediated alkenylation, alkynylation, and arylation, (2) Co/Cr-mediated 2-haloallylation, alkylation, and proparg
