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127793-62-8

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127793-62-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 127793-62-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,7,9 and 3 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 127793-62:
(8*1)+(7*2)+(6*7)+(5*7)+(4*9)+(3*3)+(2*6)+(1*2)=158
158 % 10 = 8
So 127793-62-8 is a valid CAS Registry Number.

127793-62-8Relevant articles and documents

β-elimination of a phosphonate group from an alkoxy radical: An intramolecular acylation approach using an acylphosphonate as a carbonyl group acceptor

Kim, Sunggak,Cho, Chang Ho,Lim, Chae Jo

, p. 9574 - 9575 (2003)

On the basis of facile β-elimination of a phosphonate group from an alkoxy radical, intramolecular acylation reaction has been developed, in which an acylphosphonate is used as an excellent carbonyl group radical acceptor. Copyright

New method for promoting photosensitive oxidation to remove 1, 2-mercaptoethanol acetal protecting group by utilizing visible light irradiation

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Paragraph 0014-0016, (2021/01/30)

The invention discloses a new method for removing a 1, 2-mercaptoethanol acetal protecting group, and belongs to the field of organic synthetic chemistry. The method comprises the following steps of:under a room-temperature open system, adding a substrate 2-substituted-1, 3-oxo-thio-cyclopentane and a catalytic amount of a photosensitizer Eosin Y into a proper amount of acetonitrile; and performing irradiating with a blue LED lamp for 3 hours while stirring to obtain the corresponding aldehyde compound with favorable yield. The method has the advantages of mild operation conditions, greenness, environmental protection, no harsh water and oxygen removal operation and device, realization of the reaction at room temperature, high substrate conversion rate, simple and easy post-treatment, andprovides a good method for removing the 1, 2-mercaptoethanol acetal protecting group at present.

Chemoenzymatic process for the preparation of (S)-7-((tert-butyldiphenylsilyl)oxy)hept-1-yn-4-ol in a continuous packed-bed reactor, a key intermediate for eribulin synthesis

Basetty, Shalini,Chandrasekhar, Srivari,Ghosh, Subhash,Krishna, Avula Shiva,Kumaraguru, Thenkrishnan,Mainkar, Prathama S.,Nasam, Rajesh,Pabbaraja, Srihari,Ralte, Samuel L.,Reddy, Chada Raji,Sudhakar, Gangarajula

, p. 2657 - 2664 (2020/12/29)

A practical chemoenzymatic process has been developed for the preparation of optically pure (S)-7-((tertbutyldiphenylsilyl) oxy)hept-1-yn-4-ol, (S)-4. This was prepared via enantioselective acylation of racemic homopropargylic alcohol (+/-)-4 catalyzed by

Intermediate for preparing halichondrin compound and preparation method thereof

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Paragraph 0132; 0160-161, (2020/07/07)

The invention relates to an intermediate for preparing a halichondrin compound and a preparation method thereof. The invention particularly relates to an intermediate for preparing halichondrin, eribulin or analogues thereof, and a preparation method and application of the intermediate. The intermediate as well as the preparation method and application thereof are used for constructing C20-C26 structural fragments of the halichondrin compound. The initial raw materials of the synthesis route are cheap, easy to obtain, stable in source and reliable in quality; the structural characteristics ofreactants are fully utilized in the selection of a chiral center construction method, so that the synthesis efficiency is practically improved, and the difficulty and risk of product quality control are reduced; and the use of a high-toxicity and expensive organic tin catalyst is avoided, so that the cost and the environmental friendliness are remarkably improved.

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