481063-55-2

Upstream product

• 3728-50-5 butylidenetriphenylphosphorane 
• 63-29-6 D-glucurono-6,3-lactone 
• 126214-81-1 5-O-tert-butyldimethylsilyl-1,2-O-isopropylidene-α-D glucofuraurono-6,3-lactone 
• 3067-56-9 D-glucurono-3,6-lactone acetonide 
• 481063-36-9 tert-Butyl-((3aR,3bS,5S,6R,6aS,7aR)-2,2-dimethyl-5-pentyl-hexahydro-furo[2',3':4,5]furo[2,3-d][1,3]dioxol-6-yloxy)-dimethyl-silane 
• 481063-51-8 (S)-1-((2R,3R,4S,5S)-4-Benzyloxy-3-hydroxy-5-pentyl-tetrahydro-furan-2-yl)-ethane-1,2-diol 

Relevant academic research and scientific papers

First practical asymmetric synthesis of a new tetrasubstituted tetrahydrofuran, (-)-goniothalesdiol

An efficient and practical strategy has been developed for the construction of the antipode of 3,4-dihydroxy-2,5-disubstituted tetrahydrofuran, goniothalesdiol, isolated from the bark of the Malaysian tree. The synthetic process is based on the convenient manipulation via Lewis acid-induced deoxygenation of the highly functionalized lactone derived from D-glucuronolactone.