481065-92-3 Usage
Description
1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid (SALTDATA: FREE) is a pyrazole derivative with the molecular formula C7H6F3N3O2. It contains a carboxylic acid functional group and a trifluoromethyl group, making it a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, dyes, pigments, and other specialty chemicals.
Uses
Used in Pharmaceutical Research:
1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid (SALTDATA: FREE) is used as a building block in the development of new compounds for pharmaceutical research. Its unique structure and functional groups contribute to the creation of innovative drugs with potential therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid (SALTDATA: FREE) serves as an intermediate for the synthesis of various agrochemicals. Its properties allow for the development of effective products for crop protection and pest control.
Used in Dye and Pigment Manufacturing:
1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid (SALTDATA: FREE) is utilized in the production of dyes and pigments, where its chemical structure imparts specific color and stability properties to the final products.
Used in Specialty Chemicals Production:
1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid(SALTDATA: FREE) also finds application in the manufacturing of specialty chemicals, where its unique attributes can be harnessed for specific industrial applications, such as in the development of high-performance materials or advanced chemical formulations.
Check Digit Verification of cas no
The CAS Registry Mumber 481065-92-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,1,0,6 and 5 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 481065-92:
(8*4)+(7*8)+(6*1)+(5*0)+(4*6)+(3*5)+(2*9)+(1*2)=153
153 % 10 = 3
So 481065-92-3 is a valid CAS Registry Number.
481065-92-3Relevant articles and documents
COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS
-
Page/Page column 47; 71, (2020/02/06)
The present invention relates to compounds of Formula (Ia) or pharmaceutically acceptable salts, hydrates, solvates, clathrates, polymorphs, stereoisomers thereof. It further discloses a pharmaceutical composition comprising the compounds of Formula (Ia) and the use of compounds of Formula (Ib), in particular to modulate CFTR protein or ABC protein activities.
Improved regioselectivity in pyrazole formation through the use of fluorinated alcohols as solvents: Synthesis and biological activity of fluorinated tebufenpyrad analogs
Fustero, Santos,Roman, Raquel,Sanz-Cervera, Juan F.,Simon-Fuentes, Antonio,Cunat, Ana C.,Villanova, Salvador,Murguia, Marcelo
, p. 3523 - 3529 (2008/09/20)
(Chemical Equation Presented) The preparation of N-methylpyrazoles is usually accomplished through reaction of a suitable 1,3-diketone with methylhydrazine in ethanol as the solvent. This strategy, however, leads to the formation of regioisomeric mixtures of N-methylpyrazoles, which sometimes are difficult to separate. We have determined that the use of fluorinated alcohols such as 2,2,2-trifluoroethanol (TFE) and 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as solvents dramatically increases the regioselectivity in the pyrazole formation, and we have used this modification in a straightforward synthesis of fluorinated analogs of Tebufenpyrad with acaricide activity.
