4815-67-2Relevant academic research and scientific papers
Enol esters as intermediates for the facile conversion of amino acids into amides and dipeptides
Kabouche,Bruneau,Dixneuf
, p. 5359 - 5362 (2007/10/02)
N-Protected amino enol esters are easily transformed at room temperature into amino amides, and in the presence of potassium cyanide as catalyst, into tertiary amides and dipeptides.
Amino alcohols as C-Terminal Protecting Groups in Peptide Synthesis
Kashima, Choji,Harada, Kazuo,Fujioka, Yoko,Maruyama, Tatsuya,Omote, Yoshimori
, p. 535 - 540 (2007/10/02)
The synthesis of peptides using amino alcohols as C-terminal protecting groups is described.C-Terminal protection of amino acid could be accomplished by reduction of the terminal carboxyl group to a hydroxymethyl group, and regeneration of the carboxyl group could be achieved by Jones' oxidation.This method was applied to the formation of di- and tripeptides.
