481641-93-4

Upstream product

• 3740-92-9 fenclorim 
• 13566-71-7 2-Phenyl-4,6-dihydroxy-pyrimidine 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1598384-05-4 7-chloro-2-(4-methoxyphenyl)-5-phenyl-[1,2,4]triazolo[1,5-c]pyrimidine 

Relevant academic research and scientific papers

IBD-mediated oxidative cyclization of pyrimidinylhydrazones and concurrent Dimroth rearrangement: Synthesis of [1,2,4]triazolo[1,5-c]pyrimidine derivatives

Oxidative cyclization of 6-chloro-4-pyrimidinylhydrazones 4 with iodobenzene diacetate (IBD) in dichloromethane gives rise to [1,2,4]triazolo[4,3-c]pyrimidine derivatives 5a-o. These incipient products undergo feasible Dimroth rearrangement to furnish the isolated [1,2,4]triazolo[1,5-c]pyrimidines 6a-o in moderate to high yields.