L-N-Carbobenzoxy-glutaminsaeure-α-cyanmethylester-γ-benzylester, also known as Z-Glu(OtBu)-Cbz, is a synthetic peptide protecting group used in peptide synthesis. It is a derivative of glutamic acid, where the α-carboxylic acid group is protected by a cyanomethyl group and the γ-carboxylic acid group is protected by a benzyl group. The N-terminal is also protected by a carbobenzoxy (Cbz) group. This specific combination of protecting groups allows for the controlled synthesis of peptides, as it prevents unwanted side reactions and ensures that the peptide chain is built in a stepwise manner. The use of Z-Glu(OtBu)-Cbz is particularly beneficial in solid-phase peptide synthesis, where it helps to maintain the stability of the peptide chain and facilitate the coupling of subsequent amino acids.
4821-83-4
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Basic information
- Product Name: L-N-Carbobenzoxy-glutaminsaeure-α-cyanmethylester-γ-benzylester
- Synonyms:
- CAS NO:4821-83-4
- Molecular Formula:
- Molecular Weight: 410.426
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: L-N-Carbobenzoxy-glutaminsaeure-α-cyanmethylester-γ-benzylester(CAS DataBase Reference)
- NIST Chemistry Reference: L-N-Carbobenzoxy-glutaminsaeure-α-cyanmethylester-γ-benzylester(4821-83-4)
- EPA Substance Registry System: L-N-Carbobenzoxy-glutaminsaeure-α-cyanmethylester-γ-benzylester(4821-83-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 4821-83-4(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 4821-83-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,2 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.Calculate Digit Verification of CAS Registry Number 4821-83:
(6*4)+(5*8)+(4*2)+(3*1)+(2*8)+(1*3)=94
94 % 10 = 4
So 4821-83-4 is a valid CAS Registry Number.
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L-N-Carbobenzoxy-glutaminsaeure-α-cyanmethylester-γ-benzylester
