4823-13-6Relevant academic research and scientific papers
Copper-Catalyzed three- Five- or seven-Component coupling reactions: The selective synthesis of cyanomethylamines, N,N-bis(cyanomethyl)amines and N,N'-bis(cyanomethyl)methylenediamines based on a strecker-type synthesis
Sakai, Norio,Takahashi, Nobuaki,Inoda, Daiki,Ikeda, Reiko,Konakahara, Takeo
, p. 12488 - 12499 (2013/11/06)
We have demonstrated that a cooperative catalytic system comprised of CuCl and Cu(OTf)2 could be used to effectively catalyse the three-, five- and seven-component coupling reactions of aliphatic or aromatic amines, formaldehyde, and trimethylsilyl cyanide (TMSCN), and selectively produce in good yields the corresponding cyanomethylamines, N,N-bis(cyanomethyl)amines and N,N'-bis(cyanomethyl)methylenediamines.
Preparation of N-Alkyl, 2-substituted iminodiacetic acid derivatives
Katritzky,Latif,Noble,Harris
, p. 999 - 1001 (2007/10/02)
A new method has been developed for the preparation of unsymmetrically substituted iminodiacetronitiles and iminodiacetoamides employing mild conditions and affording good overall yields.
