482376-74-9

Upstream product

• 482376-70-5 N-but-3-enyl-N-[4-but-3-enylamino-6-(tert-butyl-dimethyl-silanyloxy)-cyclohept-2-enyl]-2-nitro-benzenesulfonamide 
• 482376-67-0 N-but-3-enyl-N-[6-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-cyclohept-2-enyl]-2-nitro-benzenesulfonamide 
• 482376-68-1 N-but-3-enyl-N-[6-(tert-butyl-dimethyl-silanyloxy)-4-chloro-cyclohept-2-enyl]-2-nitro-benzenesulfonamide 
• 482376-66-9 (-)-(1S,3S,5S)-5-[N-(but-3-enyl)-N-(2-nitrobenzenesulfonyl)amino]-3-(tert-butyl-dimethylsilanyloxy)cyclohept-6-enyl acetate 
• 134734-52-4 (1R,4S,6S)-4-acetoxy-6-[(tert-butyldimethylsilyl)oxy]-2-cyclohepten-1-ol 
• 482376-72-7 [(1S,4S)-4-(Benzyloxycarbonyl-but-3-enyl-amino)-6-(tert-butyl-dimethyl-silanyloxy)-cyclohept-2-enyl]-but-3-enyl-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Enantioselective synthesis of (-)-anaferine dihydrochloride by a ruthenium-catalysed tandem ring rearrangement metathesis

A stereoselective synthesis of (-)-anaferine dihydrochloride has been developed. The bis(tetrahydropyridine) system 10 was formed by a tandem ring rearrangement metathesis of the chiral bis(but-3-enylamino) cycloheptene derivative 9 (-)-Anaferine dihydrochloride was obtained in 23% overall yield in eleven steps and its absolute configuration was confirmed as (R,R) by this total synthesis.