482376-66-9

Upstream product

• 90870-33-0 N-(2-nitrobenzenesulfonyl)-N-(but-3-enyl)amine 
• 134734-52-4 (1R,4S,6S)-4-acetoxy-6-[(tert-butyldimethylsilyl)oxy]-2-cyclohepten-1-ol 

Downstream Products

• 501415-99-2 (-)-(1S,3S,5S)-5-[N-(but-3-enyl)-N-(benzyloxycarbonyl)amino]-3-(tert-butyl-dimethylsilanyloxy)cyclohept-6-enyl acetate 
• 501416-09-7 (-)-(1S,3S,5S)-3-allyloxy-5-[N-(but-3-enyl)-N-(2-nitrobenzenesulfonyl)amino]cyclohept-6-enyl acetate 
• 501416-10-0 (-)-(1S,3S,5S)-3-allyloxy-5-[N-(but-3-enyl)-N-(benzyloxycarbonyl)amino]cyclohept-6-enyl acetate 
• 501416-07-5 (-)-(1S,3S,5S)-5-[N-(but-3-enyl)-N-(benzyloxycarbonyl)amino]-3-hydroxycyclohept-6-enyl acetate 
• 482376-72-7 [(1S,4S)-4-(Benzyloxycarbonyl-but-3-enyl-amino)-6-(tert-butyl-dimethyl-silanyloxy)-cyclohept-2-enyl]-but-3-enyl-carbamic acid benzyl ester 
• 482376-74-9 C₃₅H₄₈N₂O₅Si 
• 482376-70-5 N-but-3-enyl-N-[4-but-3-enylamino-6-(tert-butyl-dimethyl-silanyloxy)-cyclohept-2-enyl]-2-nitro-benzenesulfonamide 
• 482376-68-1 N-but-3-enyl-N-[6-(tert-butyl-dimethyl-silanyloxy)-4-chloro-cyclohept-2-enyl]-2-nitro-benzenesulfonamide 
• 482376-67-0 N-but-3-enyl-N-[6-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-cyclohept-2-enyl]-2-nitro-benzenesulfonamide 
• 501416-06-4 (-)-(1S,3S,5S)-5-[N-(but-3-enyl)-N-(2-nitrobenzenesulfonyl)amino]-3-hydroxycyclohept-6-enyl acetate 

Relevant academic research and scientific papers

Ruthenium catalyzed ring rearrangement: A rapid entry to substituted aza- and oxacycles

A ring-closing metathesis (RCM) and a ring-opening metathesis (ROM) are combined in a domino process giving access to a variety of aza- and oxacyles, equipped with highly functionalized side chains, starting from readily accessible cyclopentenyl or cycloh

Enantioselective synthesis of (-)-anaferine dihydrochloride by a ruthenium-catalysed tandem ring rearrangement metathesis

A stereoselective synthesis of (-)-anaferine dihydrochloride has been developed. The bis(tetrahydropyridine) system 10 was formed by a tandem ring rearrangement metathesis of the chiral bis(but-3-enylamino) cycloheptene derivative 9 (-)-Anaferine dihydrochloride was obtained in 23% overall yield in eleven steps and its absolute configuration was confirmed as (R,R) by this total synthesis.