482626-53-9

Upstream product

• 82387-42-6 methyl 3-methoxy-2-methyl-acrylate 
• 76526-43-7 methyl 3,3-dimethoxy-2-methylpropionate 
• 374752-87-1 C₃₉H₄₄O₉S 
• 152330-77-3 (2R,3S)-3-hydroxy-N-methoxy-5-(4-methoxybenzyloxy)-N,2-dimethylpentanamide 
• 129985-91-7 <3(2R,3S),4R,5S>-3-<3-hydroxy-5-<(4-methoxyphenyl)methoxy>-2-methyl-1-oxopentyl>-4-methyl-5-phenyl-2-oxazolidinone 
• 374753-00-1 (4S,5R)-3-[(2S,3R,4S,5S)-5-Benzyloxymethoxy-3-hydroxy-7-(4-methoxy-benzyloxy)-2,4-dimethyl-heptanoyl]-4-methyl-5-phenyl-oxazolidin-2-one 
• 201993-96-6 (2R,3S)-3-Benzyloxymethoxy-5-(4-methoxy-benzyloxy)-2-methyl-pentanoic acid methoxy-methyl-amide 
• 374752-76-8 (2R,3S)-3-Benzyloxymethoxy-5-(4-methoxy-benzyloxy)-2-methyl-pentanal 
• 482626-52-8 C₄₇H₅₂O₁₀S 
• 374752-85-9 C₄₈H₅₄O₉ 
• 482626-51-7 C₄₀H₄₆O₈ 
• 374752-79-1 [(2R,3S,4R,5S)-3-Benzyloxy-5-benzyloxymethoxy-7-(4-methoxy-benzyloxy)-2,4-dimethyl-heptyloxy]-tert-butyl-dimethyl-silane 
• 482626-39-1 (3R,4R,5S,6R,7S)-5-Benzyloxy-7-benzyloxymethoxy-9-(4-methoxy-benzyloxy)-4,6-dimethyl-nonane-1,3-diol 
• 374752-83-7 (4R,5R,6S,7R,8S)-6-Benzyloxy-8-benzyloxymethoxy-10-(4-methoxy-benzyloxy)-5,7-dimethyl-dec-1-en-4-ol 

Downstream Products

• 374752-89-3 C₃₇H₄₃IO₈ 
• 100905-89-3 pamamycin-607 
• 482626-54-0 (R)-2-[(2R,5S)-5-((1R,2S,3R,4R)-2-Benzyloxy-4,6-dihydroxy-1,3-dimethyl-hexyl)-tetrahydro-furan-2-yl]-propionic acid methyl ester 
• 374752-94-0 (R)-2-((2R,5S)-5-{(1R,2S,3R)-2-Benzyloxy-1-methyl-3-[(2R,5S)-5-(2-oxo-pentyl)-tetrahydro-furan-2-yl]-butyl}-tetrahydro-furan-2-yl)-propionic acid methyl ester 
• 374752-93-9 (R)-2-{(2R,5S)-5-[(1R,2R,3R,4R)-2-Benzyloxy-6-iodo-1,3-dimethyl-4-((E)-3-oxo-hex-1-enyloxy)-hexyl]-tetrahydro-furan-2-yl}-propionic acid methyl ester 
• 374752-92-8 (R)-2-{(2R,5S)-5-[(1R,2S,3R,4R)-2-Benzyloxy-4-hydroxy-1,3-dimethyl-6-(toluene-4-sulfonyloxy)-hexyl]-tetrahydro-furan-2-yl}-propionic acid methyl ester 
• 374752-91-7 C₃₇H₄₄O₈ 
• 482626-55-1 (R)-2-{(2R,5S)-5-[(1R,2R,3R,4R)-2-Benzyloxy-1,3-dimethyl-4-((E)-3-oxo-hex-1-enyloxy)-6-(toluene-4-sulfonyloxy)-hexyl]-tetrahydro-furan-2-yl}-propionic acid methyl ester 

Relevant academic research and scientific papers

Stereoselective synthesis of pamamycin-607

A macrodiolide antibiotic pamamycin-607 was synthesized by joining two hydroxy acid components. Three cis-2, 5-disubstituted tetrahydrofuran rings in the molecule were stereoselectively prepared by radical cyclization reactions of β-alkoxyvinyl ketone intermediates and a β-alkoxymethacrylate substrate. The key step of the synthesis is characterized by the predominant threo product formation in the radical cyclization reaction of a β-alkoxymethacrylate intermediate.