482647-07-4

Upstream product

• 475641-58-8 2,2-Dimethyl-propionic acid (2R,4aR,6S,7R,9aS)-7-hydroxy-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-6-ylmethyl ester 
• 1027925-80-9 tert-Butyl-[(2R,4aR,6S,7R,9aS)-6-(2,2-dibromo-vinyl)-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-7-yloxy]-diphenyl-silane 
• 482647-05-2 [(2R,4aR,6S,7R,9aS)-7-(tert-Butyl-diphenyl-silanyloxy)-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-6-yl]-methanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 482647-06-3 tert-Butyl-((2R,4aR,7R,9aS)-6-ethynyl-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-7-yloxy)-diphenyl-silane 

Downstream Products

• 482647-08-5 ((3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-2-ethynyl-2,3,6,7-tetrahydro-oxepin-3-yloxy)-tert-butyl-diphenyl-silane 
• 483340-39-2 1-[6-benzyloxy-7-benzyloxymethyl-3-(tert-butyl-diphenyl-silanyloxy)-2,3,6,7-tetrahydro-oxepin-2-yl]-5-[4,5-bis-benzyloxy-6-(2-benzyloxy-ethyl)-3-(4-bromo-benzyloxy)-tetrahydro-pyran-2-yl]-4-methanesulfinyl-4-methylsulfanyl-pent-1-en-3-ol 
• 483340-40-5 (2S,3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-2-{(Z)-5-[(2R,3R,4R,5S,6S)-4,5-bis-benzyloxy-6-(2-benzyloxy-ethyl)-3-(4-bromo-benzyloxy)-tetrahydro-pyran-2-yl]-3-hydroxy-4-methanesulfinyl-4-methylsulfanyl-pent-1-enyl}-2,3,6,7-tetrahydro-oxepin-3-ol 
• 482646-94-6 (Z)-5-((2S,3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-3-hydroxy-2,3,6,7-tetrahydro-oxepin-2-yl)-1-[(2R,3R,4R,5S,6S)-4,5-bis-benzyloxy-6-(2-benzyloxy-ethyl)-3-(4-bromo-benzyloxy)-tetrahydro-pyran-2-yl]-3-hydroxy-pent-4-en-2-one 
• 482647-09-6 [(3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-3-(tert-butyl-diphenyl-silanyloxy)-2,3,6,7-tetrahydro-oxepin-2-yl]-propynoic acid methyl ester 
• 482647-11-0 (Z)-3-[(2S,3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-3-(tert-butyl-diphenyl-silanyloxy)-2,3,6,7-tetrahydro-oxepin-2-yl]-prop-2-en-1-ol 
• 482647-10-9 3-[(3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-3-(tert-butyl-diphenyl-silanyloxy)-2,3,6,7-tetrahydro-oxepin-2-yl]-prop-2-yn-1-ol 
• 482646-96-8 (Z)-3-[(2S,3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-3-(tert-butyl-diphenyl-silanyloxy)-2,3,6,7-tetrahydro-oxepin-2-yl]-propenal 

Relevant academic research and scientific papers

Convergent synthesis of the BCDE-ring part of ciguatoxin

The BCDE-ring part of ciguatoxin has been convergently synthesized by a sequence of reactions involving coupling of the E-ring part having a Z-enal group with the B-ring part as an acyl anion equivalent, selective removal of a p-bromobenzyl protective gro