483340-39-2

Upstream product

• 100-39-0 benzyl bromide 
• 482647-01-8 [(2R,3R,4R,5S,6S)-4,5-Bis-benzyloxy-6-(2-benzyloxy-ethyl)-3-(4-bromo-benzyloxy)-tetrahydro-pyran-2-ylmethoxy]-tert-butyl-dimethyl-silane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 873-75-6 4-bromobenzenemethanol 
• 482646-96-8 (Z)-3-[(2S,3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-3-(tert-butyl-diphenyl-silanyloxy)-2,3,6,7-tetrahydro-oxepin-2-yl]-propenal 
• 482646-95-7 (2S,3S,4R,5R,6R)-3,4-Bis-benzyloxy-2-(2-benzyloxy-ethyl)-5-(4-bromo-benzyloxy)-6-(2-methanesulfinyl-2-methylsulfanyl-ethyl)-tetrahydro-pyran 
• 482647-03-0 (2S,3S,4R,5S,6S)-3,4-Bis-benzyloxy-2-(2-benzyloxy-ethyl)-5-(4-bromo-benzyloxy)-6-iodomethyl-tetrahydro-pyran 
• 482647-00-7 (2R,3R,4S,5S,6S)-4,5-Bis-benzyloxy-6-(2-benzyloxy-ethyl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-pyran-3-ol 
• 482646-98-0 (2R,4aR,6S,7S,8R,8aR)-7,8-Bis-benzyloxy-6-(2-benzyloxy-ethyl)-2-(4-methoxy-phenyl)-hexahydro-pyrano[3,2-d][1,3]dioxine 
• 482647-08-5 ((3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-2-ethynyl-2,3,6,7-tetrahydro-oxepin-3-yloxy)-tert-butyl-diphenyl-silane 
• 1027925-80-9 tert-Butyl-[(2R,4aR,6S,7R,9aS)-6-(2,2-dibromo-vinyl)-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-7-yloxy]-diphenyl-silane 
• 482646-99-1 (2R,3R,4S,5S,6S)-4,5-Bis-benzyloxy-6-(2-benzyloxy-ethyl)-2-hydroxymethyl-tetrahydro-pyran-3-ol 
• 482647-05-2 [(2R,4aR,6S,7R,9aS)-7-(tert-Butyl-diphenyl-silanyloxy)-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-6-yl]-methanol 
• 482647-06-3 tert-Butyl-((2R,4aR,7R,9aS)-6-ethynyl-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-7-yloxy)-diphenyl-silane 

Downstream Products

• 482646-94-6 (Z)-5-((2S,3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-3-hydroxy-2,3,6,7-tetrahydro-oxepin-2-yl)-1-[(2R,3R,4R,5S,6S)-4,5-bis-benzyloxy-6-(2-benzyloxy-ethyl)-3-(4-bromo-benzyloxy)-tetrahydro-pyran-2-yl]-3-hydroxy-pent-4-en-2-one 
• 483340-40-5 (2S,3R,6S,7R)-6-Benzyloxy-7-benzyloxymethyl-2-{(Z)-5-[(2R,3R,4R,5S,6S)-4,5-bis-benzyloxy-6-(2-benzyloxy-ethyl)-3-(4-bromo-benzyloxy)-tetrahydro-pyran-2-yl]-3-hydroxy-4-methanesulfinyl-4-methylsulfanyl-pent-1-enyl}-2,3,6,7-tetrahydro-oxepin-3-ol 

Relevant academic research and scientific papers

Convergent synthesis of the BCDE-ring part of ciguatoxin

The BCDE-ring part of ciguatoxin has been convergently synthesized by a sequence of reactions involving coupling of the E-ring part having a Z-enal group with the B-ring part as an acyl anion equivalent, selective removal of a p-bromobenzyl protective gro