4828-94-8

Usage

Uses

Used in Pharmaceutical Industry:
2-(But-3-en-2-yl)aniline is used as a key intermediate in the synthesis of various pharmaceuticals for its reactivity and functional group properties. It contributes to the development of new drugs and medicines by serving as a building block in their chemical structures.
Used in Dye Industry:
In the dye industry, 2-(But-3-en-2-yl)aniline is used as a precursor in the production of various dyes. Its chemical properties allow for the creation of a wide range of colors and hues, making it a valuable component in the formulation of dyes for textiles, paints, and other applications.
Used in Organic Compounds Synthesis:
2-(But-3-en-2-yl)aniline is used as a starting material in the synthesis of other organic compounds. Its reactivity and functional group properties make it an important building block in the production of various organic compounds for different industries, including chemical, pharmaceutical, and materials science.

Upstream product

• 6246-96-4 N-(2-buten-1-yl)aniline 
• 62-53-3 aniline 
• 69611-44-5 N-(3-methyl-2-butyne)aniline 
• 62722-94-5 (Z)-N-(but-2-en-1-yl)aniline 
• 114067-35-5 ((E)-2-butenyl)trifluorosilane 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 1211480-94-2 N-allyl-2-(but-3-en-2-yl)aniline 
• 1597592-81-8 N-(2-bromobenzyl)-2-(but-3-en-2-yl)aniline 
• 1441228-30-3 1-azido-2-(but-3-en-2-yl)benzene 
• 1326627-32-0 C₁₃H₁₅NO 
• 41652-87-3 (+/-)-N,N-dimethyl-2-(1'-methylallyl)aniline 

Relevant academic research and scientific papers

Palladium-Catalyzed Dehydrogenative Difunctionalization of Aminoalkenes with Aminals as Oxidants and Electrophiles

A novel palladium-catalyzed aminomethylamination of aminoalkenes with an aminal, functioning not only as an aminomethylation reagent but also as an oxidant, was developed. This direct and operationally simple protocol provides a fundamentally novel and unique approach toward the synthesis of 2-(2-aminoethyl)indoles and 2-(2-aminoethyl)pyrrolidines, which are important building blocks in synthetic organic chemistry. The unity of this method was highlighted by the rapid synthesis of Alosetron, a drug used for the treatment of irritable bowel syndrome.

Synthesis of a leucomitosane via a diastereoselective radical cascade

The preparation of trans-2,3-disubstituted indolines from 1-azido-2-allylbenzene derivatives via a diastereoselective radical cascade using ethyl iodoacetate and triethylborane is described. Further lactamization afforded substituted benzopyrrolizidinones

Palladium(II)-catalyzed oxidative cascade cyclization reactions of anilides and anilines: Scope and mechanistic investigations

With Pd(OAc)2/pyridine as the catalyst system and molecular oxygen as a green oxidant, acrylanilides and N-allylanilines undergo oxidative cascade cyclization to form heterocyclic rings in high yields. This methodology is applicable to acrylani

Synthesis of polycyclic nitrogen heterocycles via alkene aminopalladation/carbopalladation cascade reaction

Chemical equation presented A new method for the synthesis of tricyclic nitrogen heterocycles from N/,2-diallylaniline derivatives Is described. These transformations proceed via sequential alkene amlnopalladation of an Intermediate LnPd(Ar)(NRR') species followed by alkene carbopalladatlon of the resulting LnPd(Ar)(R) complex. Both alkene insertion steps occur in preference to C-N or C-C bond-forming reductive elimination. An unusual 1,3palladium shift occurs when 2-Allyl-N-(2-vinylphenyl) aniline Is employed as substrate, which yields a tetracyclic molecule with three contiguous stereocenters.