69611-44-5

Upstream product

• 99359-66-7 N-(3-chloro-but-2-enyl)-aniline 
• 3355-28-0 1-Bromo-2-butyne 
• 62-53-3 aniline 
• 61493-85-4 but-2-yn-1-yl methanesulfonate 

Downstream Products

• 6220-79-7 4-phenylamino-butan-2-one 
• 104829-41-6 N-but-2-ynyl-acetanilide 
• 62722-94-5 (Z)-N-(but-2-en-1-yl)aniline 
• 35755-80-7 (E)-N-(2-butenyl)aniline 
• 51338-68-2 C₁₀H₁₀N₂O 
• 25706-25-6 α-(-2-Butinyl)-phenylhydrazin 
• 1287759-55-0 N-(but-2-yn-1-yl)-N-(2-hydroxyphenyl)benzamide 
• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 22514-60-9 1,2-dihydrolepidine 
• 1007389-72-1 3-benzyl-5-ethylidene-1,3-oxazolidin-2-one 
• 60011-48-5 N-benzyl-N-(3-methyl-2-butyne)aniline 

Relevant academic research and scientific papers

DIACYLGLYCEROL KINASE MODULATING COMPOUNDS

The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.

Zinc(ii)-catalyzed intramolecular hydroarylation-redox cross-dehydrogenative coupling of N -propargylanilines with diverse carbon pronucleophiles: Facile access to functionalized tetrahydroquinolines

Zinc(ii)-catalyzed intramolecular hydroarylation-redox cross-dehydrogenative coupling of N-propargylanilines with two types of carbon pronucleophiles (nitromethane as a sp3 carbon pronucleophile and phenylacetylenes as sp carbon pronucleophiles) proceeded to give the 2-substituted tetrahydroquinolines in good yields with 100percent atomic utilization without any additional external oxidants.

AgNO2 as the NO Source for the Synthesis of Substituted Pyrazole N-Oxides from N-Propargylamines

A straightforward method for synthesizing the pyrazole N-oxides from N-propargylamines and AgNO2 through oxidation/cyclization reaction had been developed. AgNO2 was used as the NO source for the first time to synthesize pyrazole N-o

Regioselective synthesis of annulated quinoline and pyridine derivatives by silver-catalyzed 6-endo-dig cycloisomerization

3H-pyrano[3,2-f]quinoline-3-one, 4-methyl-4,7-phen-anthrolin-3(4H)-one, and 1,3-dimethylpyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione derivatives have been synthesized by hitherto unreported silver-catalyzed 6-endo-dig mode of cycloisomerization from various N-propargylated heterocyclic compounds. The silver-catalyzed reaction provides the synthesis of potential bioactive compounds in excellent yields. Georg Thieme Verlag Stuttgart - New York.

Enantioselective hydroformylation of aniline derivatives

We have developed a ligand that reversibly binds to aniline substrates, allowing for the control of regioselectivity and enantioselectivity in hydroformylation. In this paper we address how the electronics of the aniline ring affect both the binding of the substrate to the ligand and the enantioselectivity in this reaction.

Direct and selective N-monoalkynylation and N-monoalkenylation of anilines with alky(e)nyl methanesulfonates using methylmagnesium bromide as a base

Several anilines were directly N-monoalkynylated and N-monoalkenylated with alkynyl methanesulfonates and alkenyl methanesulfonates, respectively, using methylmagnesium bromide as a base in good yields with high selectivities.