483334-60-7

Basic information

• Product Name: Acetic acid, 2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxo-, Methyl ester
• Synonyms: Acetic acid, 2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxo-, Methyl ester;Methyl 2-((2-(tert-butyl)phenyl)amino)-2-oxoacetate
• CAS NO: 483334-60-7
• Molecular Formula: C₁₃H₁₇NO₃
• Molecular Weight: 235.27898
• Mol File: 483334-60-7.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Acetic acid, 2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxo-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, 2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxo-, Methyl ester(483334-60-7)
• EPA Substance Registry System: Acetic acid, 2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxo-, Methyl ester(483334-60-7)

Safety Data

• Hazardous Substances Data: 483334-60-7(Hazardous Substances Data)

Upstream product

• 5781-53-3 monomethyl oxalyl chloride 
• 6310-21-0 2-(1,1-dimethylethyl)-benzenamine 

Downstream Products

• 254751-08-1 2-((2-(tert-butyl)phenyl)amino)-2-oxoacetic acid 
• 1307704-41-1 1-(2-tert-butylphenyl)indoline-2,3-dione 
• 409369-33-1 3-{2-[(2-tert-butyl-phenylaminooxalyl)-amino]-3-methyl-butyrylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester 
• 254750-83-9 (3S)-3-[N-(N′-(2-tert-butylphenyl)oxamyl)alaninyl]amino-5-(2′,3′,5′,6′-tetrafluorophenoxy)-4-oxopentanoic acid tert-butyl ester 
• 254750-82-8 (3S)-3-[N-(N′-(2-tert-butylphenyl)oxamyl)alaninyl]amino-5-(2′,3′,5′,6′-tetrafluorophenoxy)-4-hydroxypentanoic acid tert-butyl ester 
• 254750-02-2 Emricasan 
• 868565-89-3 5-bromo-3-{2-[(2-tert-butyl-phenylaminooxalyl)-amino]-propionylamino}-4-oxo-pentanoic acid tert-butyl ester 
• 868565-78-0 2-{2-[(2-tert-butyl-phenylaminooxalyl)-amino]-propionylamino}-succinic acid 4-tert-butyl ester 

Relevant articles and documents

CASPASE INHIBITOR AND PHARMACEUTICAL COMPOSITION, USE AND THERAPEUTIC METHOD THEREOF

Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.

Reagent Design and Ligand Evolution for the Development of a Mild Copper-Catalyzed Hydroxylation Reaction

Parallel synthesis and mass-directed purification of a modular ligand library, high-throughput experimentation, and rational ligand evolution have led to a novel copper catalyst for the synthesis of phenols with a traceless hydroxide surrogate. The mild reaction conditions reported here enable the late-stage synthesis of numerous complex, druglike phenols.

Synthesis of N -arylisatins by the reaction of arynes with methyl 2-Oxo-2-(arylamino)acetates

N-Arylisatins are efficiently prepared by the reaction of 2-oxo-2-(arylamino)acetates and arynes under mild reaction conditions