254750-83-9

Basic information

• Product Name: Pentanoic acid, 3-[[(2S)-2-[[2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxoacetyl]aMino]-1-oxopropyl]aMino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)-, 1,1-diMethylethyl ester, (3S)-
• Synonyms: Pentanoic acid, 3-[[(2S)-2-[[2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxoacetyl]aMino]-1-oxopropyl]aMino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)-, 1,1-diMethylethyl ester, (3S)-;(S)-tert-butyl 3-((S)-2-(2-((2-(tert-butyl)phenyl)amino)-2-oxoacetamido)propanamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoate
• CAS NO: 254750-83-9
• Molecular Formula: C₃₀H₃₅F₄N₃O₇
• Molecular Weight: 625.6084128
• Mol File: 254750-83-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.287±0.06 g/cm3(Predicted)
• PKA: 11.14±0.46(Predicted)
• CAS DataBase Reference: Pentanoic acid, 3-[[(2S)-2-[[2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxoacetyl]aMino]-1-oxopropyl]aMino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)-, 1,1-diMethylethyl ester, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanoic acid, 3-[[(2S)-2-[[2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxoacetyl]aMino]-1-oxopropyl]aMino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)-, 1,1-diMethylethyl ester, (3S)-(254750-83-9)
• EPA Substance Registry System: Pentanoic acid, 3-[[(2S)-2-[[2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxoacetyl]aMino]-1-oxopropyl]aMino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)-, 1,1-diMethylethyl ester, (3S)-(254750-83-9)

Safety Data

• Hazardous Substances Data: 254750-83-9(Hazardous Substances Data)

Upstream product

• 68259-67-6 N-Pyruvoyl-L-alanin-methylester 
• 6310-21-0 2-(1,1-dimethylethyl)-benzenamine 
• 483334-60-7 methyl 2-[N-(2-tert-butylphenylamino)]-2-oxoacetate 
• 868565-57-5 (3S)-3-[(N-benzyloxycarbonyl)alaninyl]amino-5-(2′,3′,5′,6′-tetrafluorophenoxy)-4-oxopentanoic acid tert-butyl ester 
• 868565-58-6 (3S)-3-[(N-benzyloxycarbonyl)alaninyl]amino-5-(2′,3′,5′,6′-tetrafluorophenoxy)-4-hydroxypentanoic acid tert-butyl ester 
• 254750-81-7 (3S)-3-(alaninyl)amino-5-(2′,3′,5′,6′-tetrafluorophenoxy)-4-hydroxypentanoic acid tert-butyl ester 
• 868565-55-3 (3S)-3-[(N-benzyloxycarbonyl)-L-alaninyl]amino-5-bromo-4-oxopentanoic acid tert-butyl ester 
• 254750-82-8 (3S)-3-[N-(N′-(2-tert-butylphenyl)oxamyl)alaninyl]amino-5-(2′,3′,5′,6′-tetrafluorophenoxy)-4-hydroxypentanoic acid tert-butyl ester 
• 3408-50-2 [(N-benzyloxycarbonyl)-L-alaninyl]-L-aspartic acid [beta]-tert-butyl ester 
• 3057-74-7 L-Asp(t-Bu) 
• 254751-08-1 2-((2-(tert-butyl)phenyl)amino)-2-oxoacetic acid 

Downstream Products

• 254750-02-2 Emricasan 

Relevant articles and documents

A the graciousness favorable card lives synthetic method

A synthetic method for emricasan belongs to the technical field of drug chemical synthesis. The synthetic method comprises the steps: firstly carrying out acyl chlorination reaction on pyruvic acid and an acyl chlorination reagent to obtain pyruvoyl chlor

TREATMENT OF THE COMPLICATIONS OF CHRONIC LIVER DISEASE

Provided herein are methods and compositions for treatment of a portal hypertension and cirrhosis by administering a of a caspase inhibitor alone or in combination with current treatments for portal hypertension. Also provided are methods and compositions