483348-58-9

Upstream product

• 91375-30-3 N-(hept-2-yn-1-yl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine 
• 529409-43-6 N-(p-toluenesulfonyl)-N-(tert-butoxycarbonyl)-hept-2-yn-amine 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 98435-26-8 hept-2-yn-1-amine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 425386-34-1 N-allyl-N-(hept-2-yn-1-yl)-4-methylbenzenesulfonamide 
• 1202017-18-2 C₂₃H₂₇NO₂S 
• 529409-16-3 N-(tert-butoxycarbonyl)-hept-2-yn-1-amine 
• 529409-43-6 N-(p-toluenesulfonyl)-N-(tert-butoxycarbonyl)-hept-2-yn-amine 

Relevant academic research and scientific papers

Gold(I)-catalyzed 6-endo-dig hydrative cyclization of an alkyne-tethered ynamide: Access to 1,6-dihydropyridin-2(3H)ones

Hydrate your chemistry! Hydrative cyclization of 5-yne-ynamides in the presence of Echavarren's catalyst and p-toluenesulphonic acid (PTSA)×H2O at room temperature affords an array of 1,6-dihydropyridin-2(3H)one derivatives. Isomerization, epoxidation, and hydrogenation of the double bond and insertion of an extended π-conjugate system into the pyridinone skeleton have been successfully accomplished (see scheme; Ts=tosyl). Copyright

Rhodium-catalyzed synthesis of γ-butyrolactams and pyrrolidines via cycloisomerization of N-tethered 1,6-enynes

A rhodium-catalyzed cycloisomerization reaction of N-tethered 1,6-enynes with an intramolecular halogen shift has been developed, providing a useful process for the synthesis of stereo defined γ-butyrolactam and pyrrolidine derivatives in good to excellent yields. Effects of both electronic feature and steric structure of the substrates on the outcome of the reaction were investigated.

N-silyl-tethered radical cyclizations: a new synthesis of gamma-amino alcohols.

[reaction: see text] Various allylic and propargylic amines bearing a protecting group (PG) have been employed in N-silyl-tethered radical cyclizations. The resulting silapyrrolidine adducts could be smoothly oxidized, creating access to gamma-amino alcoh